Contract Awarded for Development Of A Single Dose Intranasal Post-Exposure Prophylaxis Vaccine For Inhalation Anthrax
Although least-seen the inhalation anthrax
is the most fatal form of all.
Historically, inhalation anthrax
was considered an occupational hazard for those working in wool and goat hair mills and tanneries (5).
1) The Sverdlovsk incident represented an unfortunate albeit useful opportunity to acquire extensive data about the pathologic findings of inhalation anthrax
obtained at autopsy from 41 patients.
anthracis spores aerosolized at the drumming event, which did not result in inhalation anthrax
but did result in gastrointestinal anthrax.
In addition to its utility in CAP, Restanza is also being investigated for the prophylactic treatment of inhalation anthrax
The results published today showed that a single dose of raxibacumab was highly effective as a treatment for inhalation anthrax
in both rabbits and monkeys," said Dr Sally D.
Two cases of naturally occurring inhalation anthrax
reported during the last two years suggest that severe forms of the disease are not readily treatable with currently available antibiotics and/or with polyclonal immunoglobulins, and that novel therapeutic agents are desperately needed.
Mr Pipe said: "Sadly a Hackney resident has died in hospital following treatment for inhalation anthrax
Heine, a scientist who had worked with Ivins on inhalation anthrax
research at Fort Detrick, said he and others on their team have testified before a federal grand jury in Washington that has been investigating the anthrax mailings for more than a year.
Breathing the spores will cause inhalation anthrax
, which is only slightly less lethal than the gastrointestinal form.
Being developed for prophylaxis and post-exposure treatment of inhalation anthrax
, Anthim has been granted Fast-Track status and Orphan Drug Designation by the FDA and is being developed under the FDA Animal Rule, a regulatory process specifically designed for the development of medical countermeasures to bioterror threats.