Food and Drug Administration has granted Orphan Drug Designation for BXCL701, an investigational orally-available systemic innate immunity
activator with dual mechanisms of action, for the treatment of Acute Myeloid Leukemia.
There are two types of immune systems: 'innate immunity
' that attacks cancer cells non-specifically in the early stage, and 'adaptive immunity' that attacks cancer cells in an antigen-specific manner.
In ONM-500, the company leverages its proprietary pH-sensitive micelle technology to deliver antigens while activating innate immunity
for the treatment of cancers caused by the human papilloma virus.
Another 23 articles include updates on such matters as antigen receptor function in the context of the nanoscale organization of the B cell membrane, the antibody response of Plasmodium falciparum: cues for vaccine design and the discovery of receptor-based antibiotics, double-stranded RNA sensors and modulators in innate immunity
, new molecular insight into immune cell development, and the gut microbiota regulation of T cells during inflammation and autoimmunity.
Biopharmaceutical company Soligenix Inc (Nasdaq:SNGX) revealed on Thursday that it expects to receive the patent from the US Patent Office titled "Novel Peptides for Treating and Preventing Immune-Related Disorders, Including Treating and Preventing Infection by Modulating Innate Immunity
" on 9 April 2019.
This was an indication for an involvement of immune cell progenitors in the bone marrow," Anette Christ, postdoctoral fellow in the Institute of Innate Immunity
of the University of Bonn explains.
In this study, an unexpected link was found among gray hair, the transcription factor MITF or Melanogenesis Associated Transcription Factor, and innate immunity
Now thoroughly revised ninth edition brings the content up-to-date with significant developments in the field, especially on the topic of innate immunity
, and improving the presentation of topics across chapters for better continuity.
Latz is considered a leader in the field of innate immunity
and he has been awarded the Gottfried Wilhelm Leibniz Prize for his work in December 2017.
is the first line of defense in resisting pathogens, which plays an indispensable role against pathogens.
The importance of innate immunity
and mucosal defence system is increasingly appreciated and may be dysregulated in asthmatics individuals.3