Istaroxime is an intravenously administered agent with a positive inotropic
agent that increases myocardial contractility through inhibition of Na+/K+-ATPase.
In addition, ICU organ support interventions, ventilation, dialysis and inotropic
support were compared for patients on quinine therapy and those treated with artesunate.
* Repeated or continuous need of inotropic
support to maintain blood pressure,
Secondly, it included many other factors such as prolong ventilation, inotropic
support and use of CRRTwhich not only showed the added benefit in predicting required supportive measures but also assist in early start of therapies to prevent irremediable damage of vital organs16-18.
In addition, in this work, the negative inotropic
effects of chemerin were antagonized with L-NAME.
Classes of drugs used in the management of acute heart failure include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers, beta blockers, digoxin, diuretics, aldosterone antagonists, nitrates, inotropic
agents, and anticoagulants.
Half of the cohort required invasive ventilatory support and 3 needed inotropic
The information recorded consisted of demographic features, clinical features, laboratory parameters, course, organ dysfunction, ventilation days, inotropic
days, hospital stay, and whether the patient died.
The activity of eNOS inhibits beta-adrenergic inotropy, whereas the activity of nNOS may exhibit a positive inotropic
effect by stimulating calcium release via the ryanodine receptor (RyR).
and negative chronotropic effects of proton pump inhibitors in isolated rat atrium.
[16-19] Adjuvant treatments such as inotropic
support, correction of metabolic disturbances and minimal handling also have invaluable roles in the management of these Neonatesneonates.
Preoperative parameters (dyslipidemia, smoking, arterial hypertension, glomerular filtration rate, preoperative arrhythmias, cerebrovascular disease and transthoracic echocardiography data) and early postoperative outcome until their discharge (inotropic
medication need, re-intervention, stroke >72 h, coma >24h, mediastinitis, treatment with statins, it seems to be still an sepsis, multiple system organ failure, death) were compared.