insulin detemir


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insulin det·e·mir

 (dĕt′ə-mîr′)
n.
A long-acting insulin analog whose structure differs from that of human insulin by the attachment of the fatty acid myristic acid at the end of the B chain in place of the amino acid threonine, used in the treatment of type 1 and type 2 diabetes.

[de(s)- (variant of de-) + t(hr)e(onine) + alteration of myr(istic acid).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
Critical appraisal of the safety and efficacy of insulin detemir in glycemic control and cardiovascular risk management in diabetics.
Her medications include insulin aspart 12 unit 3 times daily, insulin detemir 22 unit once daily, metformin 1000 mg twice daily, linagliptin 5 mg, levothyroxine 100 mcg, acetylsalicylic acid 300 mg, perindopril/indapamide 10 mg/2.5 mg, and atorvastatin 20 mg.
Low dose of insulin detemir controls glycaemia, insulinemia and prevents diabetes mellitus progression in the dog with pituitary-dependent hyperadrenocorticism.
(9) Unlike other insulins, insulin detemir is associated with modest weight loss (~0.5 kg over 26 weeks) rather than weight gain.
Drugs used by patients with diabetes also took up half of the next 10 spots in the list: gabapentin was 11th, insulin detemir was 12th, metformin was 14th, insulin lispro was 16th, and metformin-sitagliptin was 20th, according to the MEPS data.
Spending on drugs used by patients with diabetes, 2015 Insulin glargine 1 Rosuvastatin 2 Atorvastatin 4 Insulin aspart 7 Sitagliptin 8 Insulin isophane (NPH) 9 Pregabalin 10 Gabapentin 11 Insulin detemir 12 Metformin 14 Insulin lispro 16 Metformin-sitagliptin 20 The number in each bar represents the drug's place in the top 20 for spending for all drugs.
He was discharged on an insulin regimen with insulin detemir and insulin lispro with the recommendation to stop all oral glycemic agents.
Another strategy to prolong the insulin absorption is by acylation of the insulin molecule--a modification implemented in the design of the analogues insulin detemir and insulin degludec.
Meanwhile, her insulin therapy was switched to the basal-bolus regimen with premeal insulin aspart (6 U) and bedtime insulin detemir (8U).
Keywords: Insulin biphasic aspart (BIAsp), Biphasic lispro (LisproMix), Insulin degludec aspart (IDegAsp), Insulin detemir.
Insulin detemir was started in addition to metformin treatment because of diagnosis diabetes.