insulin glulisine

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insulin glu·li·sine

A rapid-acting insulin analog whose amino acid sequence differs from that of human insulin by the substitution of lysine for asparagine and glutamic acid for lysine in the B chain, used in the treatment of type 1 and type 2 diabetes.

[glu(tamic acid) + alteration of lysine.]
References in periodicals archive ?
Adjust to target in type 2 diabetes: comparison of a simple algorithm with carbohydrate counting for adjustment of mealtime insulin glulisine.
No:10124 Insulin Glulisine Injection Monocomponent Insulin Glulisine 100 Units/Ml 3 Ml Pfs
the addition of rapid-acting insulin glulisine with or without metformin injected once daily at the time of the patient's main meal (basal-plus), or three times daily at meal time (basal-bolus).
Effects of initiation and titration of a single pre-prandial dose of insulin glulisine while continuing titrated insulin glargine in type 2 diabetes: a 6-month 'proof-of-concept' study.
Rapid-acting insulin analogs include insulin aspart (NovoLog[R]), insulin lispro (Humalog[R]), and insulin glulisine (Apidra[R]).
A third insulin analog on the market, insulin glulisine (Apidra), approved in 2004, has a pharmacokinetic profile that is similar to insulin aspart and lispro, but Mr.
Insulin glulisine (Category C) has limited evidence of safe use in pregnancy.
Lankisch et al showed that in patients suboptimally controlled on basal insulin glargine, the addition of a single injection of insulin glulisine at breakfast or at the meal with the highest postprandial excursion was equally effective in reducing the A1C level.
Insulin glulisine (Apidra [R]) 20 minutes after meal in combination with basal insulin analog