insulin resistance


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insulin resistance

n.
Impaired ability of an organism or of its cells or tissues to respond effectively to insulin, as in type 2 diabetes.
References in periodicals archive ?
Developing insulin resistance can lead to type 2 diabetes, which is a metabolic condition that affects millions of people worldwide.
Here are some of the causes and treatments of insulin resistance according to infomation provided by (https://www.healthline.com/nutrition/insulin-and-insulin-resistance#related-conditions) Healthline.
Food-insecure individuals had a significantly higher insulin resistance, insulin, glucose, high-sensitivity C-reactive protein (hsCRP), cortisol, and total cholesterol compared with food-secure individuals.
'Aside from diabetes, insulin resistance also leads to cancer, obesity, fatty liver, coronary artery disease, atherosclerosis, high cholesterol, Alzheimer's (cognitive decline), neuropathy (nerve damage), hyperthyroidism, blindness, kidney failure, erectile dysfunction and retinopathy.
If this system is impaired and the body does not use insulin properly, which is called insulin resistance, individuals are likely to develop high blood sugar levels, leading to an increased risk of Type 2 diabetes, the researchers explained.
However, there is little information regarding the prevalence of insulin resistance in PD."
In addition, the FPG level was measured by the hexokinase method (Abbott Diagnostics, USA), and fasting insulin level was measured by chemiluminescence immunoassay (Cabase e411/Modular E170, USA) after the 12-hour fasting period; subsequently, homeostasis model assessment as an index of insulin resistance (HOMA-IR) was calculated using the formula FPG (mg/dL)xfasting insulin ([mu]U/mL)/405 (11).
This paper aims to briefly describe PCOS, insulin resistance and its impact on PCOS.
They found that those who reported a total meat intake above the median had a significant 49% higher odds of nonalcoholic fatty liver disease (NAFLD) (95% confidence interval, 1.05-2.13; P =.028) and 63% greater odds of insulin resistance (95% CI, 1.12-2.37, P = .011), even after adjustment for potential confounders such as body mass index, physical activity, smoking, alcohol, and saturated fat and cholesterol intake.
In order to test the association of type of meat and cooking method with NAFLD and insulin resistance, the team included 357 participants, between 40 and 70 years of age.
Insulin resistance was calculated by using homeostatic model for assessment of insulin resistance (HOMA-IR).
Large amounts of studies have shown that TZDs improve insulin sensitivity in various animal models with insulin resistance and patients with type 2 diabetes [2].

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