interferon


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Related to interferon: interleukin

in·ter·fer·on

 (ĭn′tər-fîr′ŏn′)
n.
1. Any of a group of glycoproteins that are produced by different cell types in response to various stimuli, such as exposure to a virus, bacterium, parasite, or other antigen, and that inhibit infection through mechanisms such as preventing viral replication or regulating the immune system.
2. Any of a group of synthetic glycoproteins that are structurally similar to these compounds and are used therapeutically, especially as antivirals.

interferon

(ˌɪntəˈfɪərɒn)
n
(Biochemistry) biochem any of a family of proteins made by cells in response to virus infection that prevent the growth of the virus. Some interferons can prevent cell growth and have been tested for use in cancer therapy
[C20: from interfere + -on]

in•ter•fer•on

(ˌɪn tərˈfɪər ɒn)

n.
any of various proteins, produced by virus-infected cells, that inhibit reproduction of the invading virus and induce resistance to further infection.
[1957; interfere + -on1]

in·ter·fer·on

(ĭn′tər-fîr′ŏn′)
Any of a group of proteins that are produced by animal cells in response to infection by a virus and that, in many cases, prevent replication of the virus. Some interferons trigger an immune response in the body. They have been investigated as treatment for many diseases, including certain cancers.

interferon

Immune system proteins that help to protect cells against attack by some kinds of viruses.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.interferon - an antiviral protein produced by cells that have been invaded by a virus; inhibits replication of the virus
alpha-interferon - a form of interferon that is produced endogenously and commercially for its pharmacological effects (including regulation of the immune system and antiviral and antineoplastic effects)
antiviral, antiviral agent, antiviral drug - any drug that destroys viruses
beta-interferon - a form of interferon that is produced by fibroblasts and have antiviral effects; used in the treatment of multiple sclerosis
gamma-interferon - a form of interferon that is produced by T cells and macrophages; involved in the activation of phagocytes
Translations

interferon

[ˌɪntəˈfɪərɒn] Ninterferón m

interferon

n (Chem) → Interferon nt

in·ter·fer·on

n. interferón, proteína natural liberada por células expuestas a la acción del virus que se usa en el tratamiento de infecciones y neoplasmas.

interferon

n interferón m; alpha (beta, etc.) interferon interferón alfa (beta, etc.); pegylated — interferón pegilado
References in periodicals archive ?
They were divided in to two groups, one who used interferon and the other who did not.
According to the study, about 40% of hepatitis C patients on interferon and ribavirin--an antiviral medication used in combination with interferon--were not adherent to their medication regimen, a finding that suggests such patients are at risk for progression of their disease because of their inability to eliminate the virus.
PEG-Interferon lambda is the first investigational type III interferon, the company said.
Interferon alpha-2a is administered in a fixed dose, while the dose of interferon alpha-2b is calculated according to body weight.
Many patients are currently denied beta interferon because there is no evidence that it reliably reduces long-term progression of MS.
The investigator-initiated study, conducted by researchers from the University of Tubingen in Germany, showed that at the end of 72 weeks of daily therapy, the majority of patients treated with a combination of either consensus interferon plus ribavirin or pegylated interferon alfa-2a plus ribavirin had a reduction in hepatitis RNA.
In preclinical studies, Biolex has shown that BLX-883 is comparable to commercially available alfa interferon and that it can be produced cost-effectively using Biolex' proprietary LEX System in the company's cGMP manufacturing facilities.
Interferon protects pigs from infection for least 24 hours, says Marvin Grubman of Plum Island Animal Disease Center in Greenport, New York.
In all, 58 percent of the interferon group switched to imatinib during the trial.
At multiple research sites in Canada, people with MS have been treated with interferon beta-1b for almost 13 years.
The patent, "Compositions of Highly-Purified Natural Mixtures of Type I Interferon Derived from Leukocytes and Methods", became effective February 26, 2002.

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