All positive samples had an intergenic
region II variant with an additional tandem-repeat sequence (5'-GGAATATATA-3') between the I73R and I329L genes (5).
micdadei DNA was still isolated on the two last BALs, using specific Legionella PCR (kit Diagenode[R], Diagenode s.a., Liege, Belgium) and sequencing of the 23S-5S ribosomal intergenic
spacer region, (9) but Legionella specific cultures remained negative.
The majority of these DMRs were hypermethylated and located within intergenic
Designed in silico, these fragments are modified versions of the mouse immunoglobulin loci, with human exons embedded in mouse control regions and intergenic
The length of the intergenic
spacers ranged from 0 to 5,138 bp and from 0 to 1,089 bp in Pinctada fucata martensii and Pteria penguin, respectively.
HOX antisense intergenic
RNA (HOTAIR) is a recently discovered IncRNA that plays a critical role in gene regulation and chromatin dynamics.
In the current study, one of the most significant intergenic
SNPs associated with AS was examined for the first time among the Iranian population.
Based on their genomic localization and position relative to protein-coding gene, lncRNAs are classified into the long intergenic
ncRNA (transcribed between known protein-coding genes, lincRNA), intronic lncRNA (transcribed within introns of a protein-coding gene), sense lncRNA (transcribed from a gene but lack the ability of producing protein), natural antisense transcription (transcribed across the exons of a protein-coding gene from the opposite direction, NAT), and bidirectional transcription (transcribed in opposite directions in relation to the promoter of a protein-coding gene) .
Based on their location in the reference genome, these lncRNAs were categorized into five classes: intergenic
(lncRNA located in intergenic
region), intronic (lncRNA derived wholly from intron), sense, antisense (lncRNA overlapping one or more exons of another transcript on the same or opposite strand), and bidirectional (the expression of lncRNA and a neighboring coding transcript on the opposite strand).
The majority of SNPs are located in noncoding regions including introns or intergenic
These transcripts are known to not only be produced by gene fusion but can also be formed via intergenic
If Mycoplasma species were detected, the species were identified by sequencing the 16S ribosomal (r) RNA gene and 16-23S rRNA intergenic
transcribed spacer region.