interleukin-1


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in·ter·leu·kin-1

 (ĭn′tər-lo͞o′kĭn-wŭn′)
n.
Any of a family of cytokines that are released by macrophages and other cells and stimulate the inflammatory response.
References in periodicals archive ?
The abstract, entitled, Pre-treatment Endogenous Interleukin-1 Receptor Antagonist (IL-1Ra) Levels in Metastatic Colorectal Cancer (mCRC) Patients are Associated with Clinical Outcomes After Anti-Interleukin-1a Therapy (MABp1), will be presented by renowned oncologist, Dr.
The test determines the risk of and guides therapy for the incident of OA, progression, and the severity of the disease, by identifying patients with certain variations in the Interleukin-1 gene cluster.
The PerioPredict test assesses variations in genes for interleukin-1 (IL-1), a key mediator of inflammation, and detects people who are at higher risk for moderate to severe periodontal disease.
In osteoarthritis (OA), the body produces interleukin-1 (IL-1), a protein that contributes to the breakdown of the cartilage that cushions the ends of the bones.
acnes colony count, sebum production, and several cytokines and receptors: interleukin-1 (comedogenic), interleukin-1 receptor antagonist (anticomedogenic), interleukin-10 (anti-inflammatory), tumor necrosis factor (proinflammatory), TGF-[beta] (anti-inflammatory), and melanocortin-1 receptor (expressed in healthy sebaceous glands).
If approved by the European Commission, Kineret(R) would be the first drug to directly and selectively block interleukin-1 (IL-1), a protein present in excess in RA patients that results in inflammation and joint damage.
But according to researchers at the Massachusetts Institute of Technology (MIT), the solution may be found with a better understanding of how the chemical interleukin-1 affects joint cartilage.
11 April 2014 - US genetic test developer Interleukin Genetics Inc (OTCMKTS:ILIU) said Friday that the Journal of Periodontal Research had published data further supporting the clinical value of its PerioPredict genetic risk test, assessing variations in genes for interleukin-1 (IL-1), a key mediator of inflammation, and detecting people who are at higher risk for moderate to severe periodontal disease.
The investigators have found that interleukin-1 most effectively induces sleep when it is injected into the subarachnoid space, the CSF-filled region covering the surface of the brain.
Interleukin-1 is a hormone produced by cells in the blood stream that may be important in the process of rheumatic disease, due to its potential destructive effect on bone and joint structures.