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Related to interleukin-2: Proleukin


A cytokine that is released by T cells in response to an antigen and regulates the proliferation and differentiation of natural killer cells, B cells, and other T cells. It has been used experimentally to treat cancer.
References in periodicals archive ?
The report provides comprehensive information on the Interleukin-2 Receptor Subunit Alpha (IL-2 Receptor Subunit Alpha or TAC Antigen or p55 or CD25), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
Researchers experimented with 185 patients with metastatic melanoma, who were assigned to either a combination of the peptide vaccine, which is a small portion of protein that exists on the surface of the melanoma cancer cells, and Interleukin-2, or a high dose of Interleukin-2 alone.
They found that treatment with interleukin-2 receptor antibodies reduced the risk of rejection by 49 per cent after six months, with no increased risk of infection.
HA-containing SHIV VLPs enhance Th1-type cytokine production (interferon-[gamma], interleukin-2, and interleukin-12) in both systemic and mucosal sites;
Adding to the evidence is the fact that interleukin-2 receptor-alpha has recently been linked to Graves' disease and type 1, or juvenile-onset, diabetes.
These patients didn't get drugs to kill their white blood cells and received less interleukin-2 than Rosenberg's patients did, says Cassian Yee, an immunologist at the Fred Hutchinson Cancer Research Center in Seattle.
Researchers from San Jose and New York examined the effect of interleukin-2 (Proleukin) on STIs.
Meanwhile, the interleukin-2 induced rapid proliferation of the killer T cells.