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Any of various small proteins that are produced by a variety of cell types, especially T cells and other white blood cells, and that regulate many aspects of inflammation and the immune response, including stimulating the production of white blood cells and platelets.


(Biochemistry) a substance extracted from white blood cells that stimulates their activity against infection and may be used to combat some forms of cancer


(ˈɪn tərˌlu kɪn)
any of a family of small proteins that participate in the body's defense system, esp. by promoting the growth and activation of white blood cells.
[1979; inter- + leuk (ocyte) + -in1; so called because such proteins act as agents of communication between different populations of leukocytes]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.interleukin - any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)
References in periodicals archive ?
RA is a disease of multifactorial cause with more than 60% affected by the genetic influence.9 Almost 30 genes have been found to be associated with RA susceptibility and these account for more than 50% genetic contribution of RA.10 Remaining etiology is being participated by various environmental factors like infection, obesity, smoking and other environmental pollutants.11 Among the genetic factors, interleukins play a chief role in causing inflammation that leads to progressive joint destruction.
In this study the average consumption of snuff by snuff users group was 17.1+-8.4 years and average duration of snuff placement was 90.5+-8.6 minutes per day.25 Similarly a local study assessed the proinflammatory interleukins IL-1 [alpha] and IL-6 and thyroid function in naswar users.
It is a well-established fact that cytokines affect reproductive processes, such as follicular development, ovulation, fertilisation, implantation and embryonic development.1 Cytokines concomitant with foetal and maternal interface play an imperative role in normal conception.2 Interleukins (IL) are cytokines secreted by leukocytes that act on other leukocytes.
C-reactive protein, selected interleukins, growth factors, neurofilaments, microRNA, and others, either in serum or in CSF, have been proposed as possible prognosis biomarkers [18-21].
Table 2: Median concentration of interleukins according to the WHO clinical stage of HIV.
Interleukins in Cancer Biology: Their Heterogeneous Role
Interleukins are a group of cytokines expressed by white blood cells (leukocytes).
The intrathymic environment is characterized by a complex network of paracrine, autocrine, and endocrine signals involving both interleukins and thymic peptides, which can be envisioned to operate in a synergistic network to carry the evolving T cell through its stepwise development to a mature T cell.
Crameri et al., "Interleukins, from 1 to 37, and interferon-y: receptors, functions, and roles in diseases," Journal of Allergy and Clinical Immunology, vol.
Rand Sutherland et at proposes that melatonin may worsen symptoms by stimulating mononuclear cells to produce interleukins which cause tissue to become inflamed during an allergic response.