intermediate filament


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intermediate filament

n.
Any of a group of protein filaments that are a component of the cytoskeleton in animal cells, are composed of a variety of proteins such as lamins and keratins, and provide structural support for the cytoplasm and nucleus. Intermediate filaments are intermediate in diameter between microfilaments and microtubules, the other components of the cytoskeleton.
References in periodicals archive ?
The keratins are intermediate filament proteins and are important for integrity and mechanical stability of epithelial cells with the largest number of keratin genes expressed in skin.
Peripherin, a triton-insoluble protein, is 57-kDa type III neuronal intermediate filament (nIF), particularly expressed in peripheral nervous system.
Desmin intermediate filament by Nova link polymer detection system was used, according to kit instructions.
the membrane protein [beta]-dystroglycan [38, 39] and to several other proteins such as plectin [40], ankyrin [41] and the intermediate filament protein synemin [25].
CK20 is the cytoplasmic marker and a known component on the cytokeratin subgroup of intermediate filament.
The prevalence of the association of globoside with intermediate filament networks suggested that they may participate in transport or sorting of GSLs.
Intermediate filament expression in mesotheliomas: Leimyoid mesotheliomas are not uncommon.
We have also shown that the intermediate filament system of astrocytes is an important regulator of this process.
4) Among the various families and sub-families of intermediate filament proteins, keratin is an important type due to its high molecular diversity.
1992): "The molecular biology of intermediate filament proteins", en International Review of Cytology 134: 243-279.
This wide expression and distribution of vimentin, an intermediate filament that can sustain extremely large cellular deformations, will provide stability to the HNS cells submitted to regular morphological adaptations caused by a seasonal severe arid biotope.

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