This enzyme is located on the outer side of the MIM, is FAD-dependent, and has been suggested to be a major source of ROS production in the mitochondrial intermembrane
Permeabilization of the mitochondrial outer membrane with the apoptosis-induced channels of mitochondria and intermembrane
proteins release are strongly affected by Bax level (Bajt et al.
If PpPBP functions in the final step of peptidoglycan synthesis in moss plastids, similar to that in bacteria, PpPBP must localize to the intermembrane
space of the plastid envelope.
Caspases are cysteine-containing aspartic acid-specific proteases which exist as zymogens in the soluble cytoplasm, endoplasmic reticulum (ER), mitochondrial intermembrane
space, and nuclear matrix .
m] collapse, mitochondrial permeability transition pores (PTP) are opened, leading to cytochrome c and other proapoptotic molecules released, from intermembrane
space to cytosol.
Complex I leaks electrons in the intermembrane
space to generate mitochondrial anion superoxide ([O.
It is present in all human cells in various locations, including the cytosol, nucleus, peroxisomes, and mitochondrial intermembrane
Sample and Golovin employed this condition in [29 30] to study the dynamics of a double-lipid bilayer membrane by coupling intermembrane
separation and the lipid chemical composition of a two-component membrane and dependence on the membrane curvatures.
This event triggers the release of pro-apoptotic proteins, including cytochrome C, from the mitochondrial intermembrane
space to the cytosol where they activate caspases and endonucleases that initiates apoptosis.
Structurally, mitochondria have four compartments: the outer membrane, the inner membrane, the intermembrane
space, and the matrix (the region inside the inner membrane, see Figure 2, (30; 33; 34).
This experiment investigated the copper and zinc SOD and the manganese SOD found in the mitochondrial intermembrane
space and mitochondrial matrix respectively.
In addition, CoQ10 also allows protons to be extruded from the mitochondrial matrix to the intermembrane
space (3), acts as a pro- or antioxidant (4), and has a role in pyrimidine biosynthesis (5) and apoptosis modulation (6).