Comparative efficacy of endovascular revascularization versus supervised exercise training in patients with intermittent claudication
: meta-analysis of randomized controlled trials.
class="MsoNormalspan xml:lang="EN-GBTo explain the technical terms used by Dr Bosire, intermittent claudication
' means pain in the calf muscles on walking, which subsides with rest but resumes on walking again.
Also, regular exercise increases serum levels of high-density lipoprotein (HDL-cholesterol), decreased serum triglycerides, reduction in total body fat, reduction of adhesiveness and aggregation of blood platelets, reduction in inflammation, and the delay in intermittent claudication
and leg pain (24,30,35).
We described the case of a 41-year-old woman who presented with exercise-related intermittent claudication
. Although the patient experienced unilateral symptoms, a bilateral diminished blood flow was found after exercise, as shown by reduced ankle-brachial index, with tendency towards worse flow at the symptomatic side.
They commonly present with symmetrical intermittent claudication
of lower limbs.
Blevins, "Efficacy of quantified home-based exercise and supervised exercise in patients with intermittent claudication
: a randomized controlled trial," Circulation, vol.
A completely separate group of researchers conducted a similar, but smaller, randomized clinical trial of ramipril in patients with intermittent claudication
. (4) In this study, 33 patients were randomized to ramipril or placebo for a 24-week trial.
An ongoing Phase 2 trial in intermittent claudication
is expected to complete enrollment of its target of 170 patients by the end of 2016.
(3) The lower limb ischaemia presents as two distinct clinical entities: intermittent claudication
and critical limb ischaemia.
6 Intermittent claudication
due to furring up of the arteries supplying your lower leg.
L-carnitine has been shown in clinical trials to improve angina, intermittent claudication
, and congestive heart failure.
Aetiology of night cramp The condition tends to occur in the older age group, and perhaps for that reason is confused with the pain of intermittent claudication
. The two conditions are not at all associated however.