With parenteral administration, intramuscular
(IM) is the preferred approach because it increases the bioavailability of the drug, acts more quickly than the enteric route, and can be administered when enteric administration is impossible (e.g., in cases of vomiting, an uncooperative or unconscious patient, etc.).1,2 In this method of administration, drugs are often administered into the deltoid or gluteal muscles, which is the commonly selected region thanks to safety, ease of application, less pain compared to the deltoid site, and more volume of drug delivered.1,3 Medication injected into the gluteal region is absorbed almost completely and reaches the target site through the vena cava inferior without entering the enterohepatic cycle.
Past studies advocate the administration of intramuscular
injections as safe, and as effective as oral steroid therapy, suggesting it as an effective alternative for patients with asthma or COPD who are at high risk for non-adherence or unwilling to take oral therapy.16,21-25 We postulate a single dose of methylprednisolone in our population is a safe strategy at the time of discharge after acute exacerbation of asthma and COPD.
Gold label has a marbling score* of 6 to 7, which has a fairly high amount of fine intramuscular
fat, translating into that melt-in-the-mouth buttery Wagyu texture.
However, there are few reports about the effects of different cooking ways on its composition of intramuscular
phospholipid fatty acids.
Cleft Lip Repair Using Intramuscular
Hydroxyzine Sedation and Local Anesthesia.
According to the company, the maximum and total plasma levels (Cmax and AUC) were similar to intramuscular
delivery and exceeded the total plasma levels for ODT.
Amoxicillin was then injected as a single intramuscular
dose of 15mg/kg body weight to each animal (Rasheed et al., 2013).
A 100% treatment success rate (n = 66) was seen for both nasal glucagon and intramuscular
glucagon, defined as an increase in plasma glucose to 70 mg/dL (3.9 mmol/L or greater) or more or an increase of 20 mg/L (1.1 mmol/L) or more from the glucose nadir within 30 minutes of administration.
Women beyond 37 weeks of gestation, in labor with a singleton cephalic presentation, who requested opioid pain relief were randomized to intravenous remifentanil PCA (201 women) or intramuscular
pethidine (199 women).
Today the applications of intramuscular
injections have to be in line with the current best practice guidelines, which are periodically revised according to the existing evidence obtained by studies [1, 3, 4].
Only a case study of 10 patients with NSTIs after intramuscular
injections has been reported in a recent work .