In related news, the company on May 31 presented a poster of its "Phase 2 Open-Label, Multicenter Study of Repeated Intrathecal
Administration of Autologous MSC-NTF cells in Progressive Multiple Sclerosis (MS)" at the annual meeting of the Consortium of Multiple Sclerosis Centers, in Seattle, Wash.
Some studies compared the effect of intrathecal
nalbuphine with intrathecal
fentanyl in caesarean section.
MITIGO is an opioid agonist, for use in continuous microinfusion devices indicated only for intrathecal
or epidural infusion for the management of intractable chronic pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
The rabbits were sacrificed 30 min, 1 h, and 24-h post intrathecal
Many have received two intrathecal
treatments, with some completing all three.
Elliotts B Solution (buffered intrathecal
electrolyte/dextrose injection) is indicated as a diluent for the intrathecal
administration of methotrexate sodium and cytarabine for the prevention or treatment of meningeal leukemia or lymphocytic lymphoma.
Despite these limitations, this study is valuable in that it is the first study to evaluate glymphatic function in patients with INPH by using intrathecal
contrast injection and that results provide considerable perspectives.
CSF analysis demonstrated leukocytes 1 cell/[mm.sup.3]; protein 29 mg/dL; glucose 40 mg/dL; blood-CSF barrier function based on albumin quotient 6 x [10.sup.-3]; IgG index 0.43 (reference <0.7); and intrathecal
IgG fraction ([IgG.sub.IF]) of total IgG found in CSF, <0% (6,7).
Multiple-factor analysis was done using COX risk analysis regression model, and the factors included the age of onset, the severity of CNS symptoms, EBV infection, the intrathecal
injection, and the allogeneic-hematopoietic stem cell transplantation (allo-HSCT).
Neuronal injury was associated with intrathecal
chemotherapy," the authors write.
By week 9, the patient was completely weaned off oral baclofen and her spasticity and dystonia were being adequately treated with an intrathecal
baclofen total daily dose of 234.15 meg/ d.