intrinsic factor

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Related to intrinsic factor: extrinsic factor, pernicious anemia, Intrinsic pathway

intrinsic factor

A glycoprotein that is secreted by the gastric mucous membrane and is essential for the absorption of vitamin B12 in the intestines.

intrinsic factor

(Biochemistry) biochem a glycoprotein, secreted by the stomach, the presence of which is necessary for the absorption of cyanocobalamin (vitamin B12) in the intestine

intrin′sic fac`tor

a gastric glycoprotein involved in the absorption of vitamin B12.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.intrinsic factor - a substance produced by the mucosa of the stomach and intestines that is essential for the absorption of vitamin B12; "lack of intrinsic factor can result in pernicious anemia"
factor - anything that contributes causally to a result; "a number of factors determined the outcome"

in·trin·sic fac·tor

n. factor intrínseco, proteína normalmente presente en el jugo gástrico humano.
References in periodicals archive ?
This belief is still being propagated, as this quote from an article published recently attests: "Pernicious anemia is caused by inadequate secretion of gastric intrinsic factor necessary for vitamin [B.
Intrinsic factor is a protein that makes its way into the intestines to be available for a later step in the [B.
Intrinsic factor antibody testing, automated diagnosis of pernicious anemia.
While the extrinsic motivation provided by the grading system may stimulate greater effort by some students, others may be motivated by intrinsic factors.
Pernicious anaemia is B12 deficiency arising from the lack of intrinsic factor required for the enteric absorption of the vitamin.
Results based on data from 87 respondents indicated a three-factor structure among this population, including an intrinsic factor, an extrinsic factor, and another factor pertaining to satisfaction derived specifically from participating in vocational rehabilitation.
Our study suggests that age, an intrinsic factor, may play an important role in determining the behavior of larval X.
The intrinsic factor indicated to what extent coaching is engaged in due to fun or enjoyment motives.
It is due to the malabsorption of Vitamin B12 resulting from lack of special factor called Intrinsic Factor, which the body needs to absorb the vitamin from food.
Medical dictionaries define pernicious anemia as "a severe anemia caused by the failure of the gastric mucosa to secrete the intrinsic factor necessary for the absorption of vitamin [B.
Pernicious anemia has its own definition: "A severe anemia caused by the diminution or absence of stomach acid secretion, with consequent failure of the gastric mucosa to secrete the intrinsic factor necessary for the absorption of vitamin [B.
Manufacturers of automated vitamin B12 assays recommend that patients be tested for intrinsic factor antibodies if test results for serum vitamin B12 conflict with the clinical diagnosis.

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