intron


Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.

in·tron

 (ĭn′trŏn)
n.
A segment of a gene situated between exons that is removed before translation of messenger RNA and does not function in coding for protein synthesis.

[intr(agenic), occurring within a gene (intra- + genic) + -on.]

intron

(ˈɪntrɒn)
n
(Genetics) biochem a stretch of DNA that interrupts a gene and does not contribute to the specification of a protein. Compare exon2
[C20: from intr(agenic) (regi)on]

in•tron

(ˈɪn trɒn)

n.
a noncoding segment in DNA that interrupts a gene-coding sequence or nontranslated sequence. Compare exon.
[1975–80; perhaps intr (o)- + -on1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.intron - sequence of a eukaryotic gene's DNA that is not translated into a protein
deoxyribonucleic acid, desoxyribonucleic acid, DNA - (biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information; "DNA is the king of molecules"
coding DNA, exon - sequence of a gene's DNA that transcribes into protein structures; "exons are interspersed with introns"
Translations
intron
References in periodicals archive ?
As an initial step to investigate variations in OGT between European and Chinese pig breeds, attempts were made to amplify across several relatively short introns and a polymorphism was identified due to an inserted element in intron 20 of OGT [15].
A VNTR in intron 4 of eNOS gene is responsible for production of more than 25% of basal plasma NO.
Average Shannon entropy for each genomic feature [exon, intron, or untranslated region (UTR)] of HLA-A, HLA-B, and HLA-C was calculated by dividing the sum of Shannon entropy over the feature divided by the total length of the genomic feature.
01 IU mL-1 (< 1% of normal levels) (2) and is commonly caused by the intron 22 inversion (frequency of approximately 45%) (3) or the intron 1 inversion (frequency of approximately 2%) (4) in the F8 gene; the rest of the causative mutations is greatly diverse.
fragment I (206 bp: full exon 1), fragment II (296 bp: partial intron 1), fragment III (287 bp: full exon 2), fragment IV (227 bp: partial intron 2 and full exon 3), fragment V (226 bp: partial intron 3), fragment VI (201 bp: initial partial exon 4) and fragment VII (405 bp: remaining partial exon 4) of [[beta].
Moiz Bakhiet, Dr Noureddine Ben Khalaf and Dr, Safa Taha and myself are very excited because we succeeded in generating two types of transgenic mouse as a continuation of the discovery few years ago at Al Jawhara Centre of" ISRAA" an atypical gene [an intron embedded gene] that could link the Central Nervous System and the Immune System and control the outcome of infectious diseases and other major pathologies such as cancers.
In addition to skipping and inclusion of variable exons and usage of alternative splice sites,3 intron retention is a third example of alternative splicing, whereby an intron sequence is retained or skipped in the mature mRNA transcript.
At the Stanford Molecular Pathology Laboratory, the CFTR gene sequencing assay covers 983 bases of the 5' untranslated region, exons 1 to 24 (24 exons by conventional legacy nomenclature, which includes 27 factual exons), at least 20 bases into the 5' and 3' ends of all introns, the CFTR poly T and TG tracts in intron 8, intron 19 surrounding the c.
Results: Carrier detection and prenatal diagnosis was feasible with STR marker at intron 44 in DMD families.
M2 EQUITYBITES-8 April 2010-TenCate and INTRON sign cooperation agreement for certification of synthetic turf systems(C)2010 M2 COMMUNICATIONS http://www.
Statistical analyses were conducted and correlation coefficients between different variables (total gene length, exon length and intron length) were compared across taxa.