hyaluronidase

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hy·a·lu·ron·i·dase

 (hī′ə-lo͝o-rŏn′ĭ-dās′, -dāz′)
n.
An enzyme that catalyzes the breakdown of hyaluronic acid in the body, thereby increasing tissue permeability to fluids. Also called spreading factor.

hyaluronidase

(ˌhaɪəlʊˈrɒnɪˌdeɪs; -ˌdeɪz)
n
(Biochemistry) an enzyme that breaks down hyaluronic acid, thus decreasing the viscosity of the medium containing the acid
[C20: hyalo- + Greek ouron urine + -id3 + -ase]

hy•a•lu•ron•i•dase

(ˌhaɪ ə lʊˈrɒn ɪˌdeɪs, -ˌdeɪz)

n.
an enzyme that decreases viscosity in the tissue spaces of the body by breaking down hyaluronic acid: used as an ingredient for diffusing injected drugs.
[1935–40; hyaluron(ic acid) + -id- + -ase]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.hyaluronidase - an enzyme (trade name Hyazyme) that splits hyaluronic acid and so lowers its viscosity and increases the permeability of connective tissue and the absorption of fluids
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
References in periodicals archive ?
Major organization : FUNDACIN CENTRO DE CIRUGA DE MNIMA INVASIN JESS USN (G10347417)
They encode an invasin, which directly initiates cell penetration, and an outer membrane protein called Ail, which encodes a factor that also promotes the invasion of epithelial cells, respectively.
Analysis of Yersinia enterocolitica invasin expression in vitro and in vivo using a novel luxCDABE reporter system.
This protein is essential for invading the host cell membrane; the ORF for invasin was mutated at four sites, creating four non-functional ORFs.
Similarly, the adhesive protein invasin from Yersinia pseudotuberculosis promotes bacteria crossing the intestine epithelium by binding to [beta]1 integrins on M-cells.
Zychlinsky, "The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1," Proceedings of the National Academy of Sciences of the United States of America, vol.
The hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin.
They included adhesins (papC, sfaDE, afaBC III, iha, fimH, and clpG), invasin (ibe10), elements involved in iron acquisition (iucD, irp2,andchuA), protectins (iss, traT, cvaC, kpsMT II, and kpsMT III), and toxins (ompT, ehxA, espP, hlyA,andcnf1).
The Yersinia bacteria contain invasin as a surface protein to help them penetrate the intestinal cells, leading to heavy bouts of diarrhoea.