hydatidiform mole

(redirected from invasive mole)
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Noun1.hydatidiform mole - an abnormality during pregnancyhydatidiform mole - an abnormality during pregnancy; chorionic villi around the fetus degenerate and form clusters of fluid-filled sacs; usually associated with the death of the fetus
abnormalcy, abnormality - an abnormal physical condition resulting from defective genes or developmental deficiencies
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Gestational trophoblastic disease (GTD) is a spectrum of disorders extending from premalignant conditions of hydatidiform mole, which can be further classified into partial (PHM) and complete (CHM) hydatidiform mole, to malignant conditions including invasive mole, choriocarcinoma, and placental site trophoblastic tumor (PSTT).
The algorithms he referred to were established by a handful of centers with expertise and experience in diagnosing and treating these rare conditions, including noninvasive hydatidiform mole, invasive mole, and choriocarcinoma, the most aggressive form of GTN.
Gestational trophoblastic disease is a group of disorders caused by the overgrowth of placental tissue and is defined as the spectrum of disease that has at one extreme the benign hydatidiform mole which could be complete or partial mole, the locally Invasive mole, Placental site trophoblastic tumor, Gestational tropho-blastic neoplasia and at the other end, the highly malignant Choriocarcinoma, based on genetic and histopathological features1.
Background: Invasive mole is responsible for most cases of localized gestational trophoblastic neoplasia.
GTN includes molar pregnancy, invasive mole, choriocarcinoma and placental site trophoblastic neoplasia with varying degrees of malignant potential.
It has a wide clinical spectrum consisting of partial (PM) and complete hydatidiform mole (CM), invasive mole, choriocarcinoma, and placental site trophoblastic tumor.
Histologically, GTD includes complete mole, partial mole, invasive mole, placental site trophoblastic tumor and choriocarcinoma.
Gestational trophoblastic disease (GTD) refers to an abnormal trophoblastic proliferation composed of a broad spectrum of lesions ranging from benign, albeit premalignant hydatiform mole (complete and partial), through to the aggressive invasive mole, choriocarcinoma, and placental site trophoblastic tumor (PSTT).
reported a case of a third partial molar pregnancy that they considered to be at risk for an invasive mole after the previous evacuation, therefore, they treated the patient with prophylactic chemotherapy.
The diagnosis of hydatidiform mole is clinically important because of its potential to give rise to persistent gestational trophoblastic disease including invasive mole, choriocarcinoma and placental site trophoblastic tumors.
(5) It was shown to predominate in early pregnancy-serum samples, to be directly associated with the implantation of pregnancy, to be associated with invasion in invasive mole, and gestation-trophoblastic neoplasms including choriocarcinoma.
Bleeding is one of the most common clinical presentations of this spectrum of disorders that includes hydatidiform mole, invasive mole, and choriocarcinoma.

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