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Noun1.iodotyrosine - tyrosine with iodine added
iodoamino acid - an amino acid with iodine added
mono-iodotyrosine - tyrosine with one iodine atom added
di-iodotyrosine - tyrosine with two iodine atoms added
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References in periodicals archive ?
Due to rapid internalization after renal and hepatic uptake, [[sup.125]I]I-DARPin 9_29 undergoes lysosomal degradation, and the main radiometabolite, iodotyrosine, "leaks" from cells.
Approximately 15-20% of CH cases result from thyroid dyshormonogenesis (DH) caused by mutations in thyroid hormone synthesis pathway genes, including those involved in hormone precursor production (thyroglobulin (TG)) [2], iodine transportation across the basal membrane (solute carrier family 5 member 5 (SLC5A5) [3], solute carrier family 26 member 4 (SLC26A4) [4]), thyroglobulin modification (thyroid peroxidase (TPO) [5], dual oxidase 2 gene (DUOX2) [6], and dual oxidase maturation factor 2 (DUOXA2) [7]), and iodine recycling in the thyroid (iodotyrosine deiodinase (IYD)) [8].
Thyroid peroxidase (TPO) is essential for various steps in thyroid hormone synthesis, iodine oxidation, iodination of tyrosine residues, and coupling of iodotyrosine. TPO is located at the apical membrane of the thyroid follicles.