islets of Langerhans


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Related to islets of Langerhans: insulin, pancreas, somatostatin

is·lets of Lang·er·hans

 (ī′lĭts; läng′ər-häns′)
pl.n.
Irregular clusters of endocrine cells scattered throughout the tissue of the pancreas that secrete insulin and glucagon. Also called islands of Langerhans.

[After Paul Langerhans (1847-1888), German pathologist.]

islets of Langerhans

(ˈlæŋəˌhæns) or

islands of Langerhans

pl n
(Anatomy) small groups of endocrine cells in the pancreas that secrete the hormones insulin and glucagon
[C19: named after Paul Langerhans (1847–88), German physician]

is·lets of Lang·er·hans

(ī′lĭts əv läng′ər-häns′)
Irregular clusters of endocrine cells that are scattered throughout the tissue of the pancreas and secrete insulin.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.islets of Langerhans - cell clusters in the pancreas that form the endocrine part of that organ; secrete insulin and other hormones
ductless gland, endocrine gland, endocrine - any of the glands of the endocrine system that secrete hormones directly into the bloodstream
pancreas - a large elongated exocrine gland located behind the stomach; secretes pancreatic juice and insulin
References in periodicals archive ?
Westermark, "Fine structure of islets of Langerhans in insular amyloidosis," Virchows Archiv A: Pathologische Anatomie, vol.
Lovari et al., "Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN beta cell line and human islets of Langerhans," The FASEB Journal, vol.
In Type I diabetes, the insulin-producing islets of Langerhans, scattered throughout the pancreas, are selectively destroyed by an apparent autoimmune process.
Neuroendocrine reasons include disorders of the autonomic ner vous system (leading to hypoglycaemia unawareness), pancreas (glucagon deficiency/due to destruction of islets of Langerhans, and exocrine enzyme deficiency, due to destruction of exocrine pancreas) and other glands which secrete counter-regulatory hormones (e.g.; cyclical Cushing's, pheochromocytoma, changes in thyroid function while using thyrotropic medication).
A major component of the endocrine function of the pancreas involves the production of two hormones that are produced in cells called the islets of Langerhans. The first hormone is glucagon, which increases blood glucose, the preferred energy source for bodily functions.
Pancreatic sections from normal mice exhibited islets of Langerhans cells, and contained lightly stained acidophilic cells arranged in branching and anastomosing cords (Figure 6A).
These cells exist in clusters called islets of Langerhans, which contain several types of cell that make hormones.
Thyroid hormones, gonadal and adrenocortical steroid and the function of islets of langerhans. Endocr Rev 1984; 5:411-34.
The "small but certain happiness" concept, borrowed from famous Japanese writer Haruki Murakami in his essay "Afternoon in the Islets of Langerhans." He described a small piece of happiness as eating a freshly-baked loaf of bread with one's hands, seeing neatly folded underwear in a drawer, wearing a new shirt that smells like clean cotton and letting a cat enter into a bed with a rustling sound.
Induction of insulin secretion by a component of Urtica dioica leave extract in perifused Islets of Langerhans and its in vivo effects in normal and streptozotocin diabetic rats.
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