isocarboxazid

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Related to isocarboxazid: Linezolid, Selegiline, tranylcypromine

i·so·car·box·a·zid

(ī′sō-kär-bŏk′sə-zĭd)

A monoamine oxidase inhibitor, C₁₂H₁₃N₃O₂, used as an antidepressant.

[Shortening and rearrangement of isoxazolylcarbonyl, one of its constituents + (hydr)azid(e), one of its constituents; see isoniazid.]

isocarboxazid

(ˌaɪsəʊkɑːˈbɒksəzɪd)

(Recreational Drugs) an antidepressant that is derived from hydrazine. Formula: C12H13N3O2

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Noun

isocarboxazid - a monoamine oxidase inhibitor (trade name Marplan) that is used to treat clinical depression

Marplan

MAOI, monoamine oxidase inhibitor - any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate

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2) The Sequenced Treatment Alternatives to Relieve Depression (STARED) study demonstrated that <50% of MDD patients achieve remission in monotherapy trials of selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, mirtazapine, or bupropion, necessitating consideration of antidepressant combinations, augmentation options, and eventually irreversible, nonselective MAOIs such as phenelzine, tranylcypromine, or isocarboxazid.

A concise guide to monoamine oxidase inhibitors: A better understanding of the risks can lead to increased use of these highly effective agents

Monoamine phenelzine (Nardil); Increase oxidase tranylcypromine (Parnate); norepinephrine, inhibitors isocarboxazid (Marplan) serotonin, and (MAOIs) dopamine.

The best treatments for depression and anxiety

5 75-225 Serotonin modulators Trazodone 50 75-400 Norepinephrine-serotonin modulator (NaSSA) Mirtazapine 15 15-45 Monoamine oxidase inhibitors (MAOIs) Irreversible, nonselective Phenelzine 15 15-90 Tranylcypromine 10 30-60 Isocarboxazid 20 30-60 Reversible MAOI-A Moclobemide 300 300-600 Melatonergic agonist Agomelatine 25 25-50 * Reprinted with permission from APA Practice Guideline for the Treatment of Patients with Major Depressive Disorder, 3rd ed, [c] 2010).

Major depressive disorder

They include phenelzine (Nardil), isocarboxazid (Marplan) and tranylcypromine (Parnate).

Depression

A recent meta-analysis (2) found no benefit over placebo of the ADs paroxetine, fluoxetine, amitriptyline and isocarboxazid - studied specifically in patients with 'minor' depression.

Issues in treating depression in primary care: the last decade has provided a better evidence base for treating depression

MAO inhibitor antidepressants (for example, isocarboxazid and moclobemide).

Could a drink be making your pills hard to swwallow? EVERYTHING FROM EATING TOO MUUCH SPINACH TO DRINKING A SIMPLE GLASS OF F MILK CAN AFFECT HOW PRESCRIPTION DRUGS S WORK AND, IN SOME CASES, IT CAN BE A LIFE-THREATENING MIX

1A] receptor agonist used for anxiety) may interact with monoamine oxidase inhibitors (MAOIs), such as isocarboxazid, phenelzine, and tranylcypromine.

Over-the-counter and purchase-on-internet medications--implications for psychiatry

phenelzine, isocarboxazid, tranylcypromine) potentiate brain amine levels by inhibiting the breakdown of brain amines.

Tinospora cordifolia: role in depression, cognition and memory

The first-generation MAOIs such as phenelzine and isocarboxazid were largely nonselective inhibitors of both subtypes of MAO, MAO (A) and MAO (B).

Food-drug interactions

PHILADELPHIA--The monoamine oxidase inhibitor isocarboxazid may be an effective migraine preventive as well, Dr.