isocarboxazid


Also found in: Thesaurus, Medical, Wikipedia.
Related to isocarboxazid: Linezolid, Selegiline, tranylcypromine

i·so·car·box·a·zid

 (ī′sō-kär-bŏk′sə-zĭd)
n.
A monoamine oxidase inhibitor, C12H13N3O2, used as an antidepressant.

[Shortening and rearrangement of isoxazolylcarbonyl, one of its constituents + (hydr)azid(e), one of its constituents; see isoniazid.]

isocarboxazid

(ˌaɪsəʊkɑːˈbɒksəzɪd)
n
(Recreational Drugs) an antidepressant that is derived from hydrazine. Formula: C12H13N3O2
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.isocarboxazid - a monoamine oxidase inhibitor (trade name Marplan) that is used to treat clinical depressionisocarboxazid - a monoamine oxidase inhibitor (trade name Marplan) that is used to treat clinical depression
MAOI, monoamine oxidase inhibitor - any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate
References in periodicals archive ?
The National Pregnancy Registry for Antidepressants (844-405-6185) is studying amitriptyline (Elavil), amoxapine (Asendin), bupropion (Forfivo XL and Wellbutrin), Citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), desvenlafaxine (Prisiq), doxepin (Sinequan), escitalopram (Lexapro), fluvoxamine (Luvox), fluoxetine (Prozac), imipramine (Tofranil), isocarboxazid (Marplan), levomilnacipran (Fetzima), maprotiline (Ludiomil), mirtazapine (Remeron), nefazodone (Serzone), nortriptyline (Pamelor), paroxetine (Paxil), phenelzine (Nardill), protriptyline (Vivactil), selegiline (Emsam), sertraline (Zoloft), tranylcypromine (Parnate), trazodone (Desyrel), trimipramine (Surmontil), venlafaxine (Effexor), and vilazodone (Viibryd).
Edema has been reported during treatment with various antidepressants such as mirtazapine, trazodone, tranylcypromine, phenelzine and isocarboxazid (13-15).
MAO inhibitors including tranylcypromine, isocarboxazid, phenelzine, and moclobemide are often used as first-line therapy [7].
Monoamine phenelzine (Nardil); Increase oxidase tranylcypromine (Parnate); norepinephrine, inhibitors isocarboxazid (Marplan) serotonin, and (MAOIs) dopamine.
They include phenelzine (Nardil), isocarboxazid (Marplan) and tranylcypromine (Parnate).
A recent meta-analysis (2) found no benefit over placebo of the ADs paroxetine, fluoxetine, amitriptyline and isocarboxazid - studied specifically in patients with 'minor' depression.
Buspirone (a [5-HT.sub.1A] receptor agonist used for anxiety) may interact with monoamine oxidase inhibitors (MAOIs), such as isocarboxazid, phenelzine, and tranylcypromine.
phenelzine, isocarboxazid, tranylcypromine) potentiate brain amine levels by inhibiting the breakdown of brain amines.
The first-generation MAOIs such as phenelzine and isocarboxazid were largely nonselective inhibitors of both subtypes of MAO, MAO (A) and MAO (B).
PHILADELPHIA--The monoamine oxidase inhibitor isocarboxazid may be an effective migraine preventive as well, Dr.