isochromosome

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isochromosome

(ˌaɪsəʊˈkrəʊməˌsəʊm; ˌaɪsəʊˈkrəʊməˌzəʊm)
n
(Biology) cytology an abnormal chromosome in which the two arms share identical genetic information
References in periodicals archive ?
Homologous rearrangements of acrocentric chromosomes can result in either isochromosomes or ROBs (24).
It is likely that a complete genomic characterization of CLL requires a combination of fluorescence in situ hybridization (FISH), single nucleotide polymorphism (SNP) array profiling for comprehensive genome-wide analysis of acquired genomic copy number aberrations (aCNAs) and loss-of-heterozygosity (LOH) in dominant clones, and karyotyping for detection of balanced translocations, isochromosomes, and marker chromosomes.
Stahlschmidt and colleagues reported several numerical and structural chromosome changes, including isochromosomes for 1q, 8q and 17q, translocation between chromosomes 10 and 16, and between chromosomes 9 and 22, and rearrangement of the chromosomes 22 at q11.
Polysomy and supernumerary isochromosomes in the grasshopper Omocestus bolivari (Chopard).
In addition to the reconstructed chromosomes 2B and 2R, among the progeny screened there were several plants with telocentric chromosomes 2RS, 2RL, 2BS, or 2BL, with isochromosomes 2RS, 2BS, and 2BL, and centric translocations 2BS.2RS and 2BL.2RL (Fig.