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An isoantibody normally present in the serum of an individual that causes the agglutination of the red blood cells of another individual of the same species.


(Biology) an antibody that causes agglutination of red blood cells in animals of the same species from which it was derived


(ˌaɪ soʊ əˈglut n ɪn)

an agglutinin that can effect isoagglutination.
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Noun1.isoagglutinin - an antibody produced by one individual that causes agglutination of red blood cells in other individuals of the same species
agglutinin - an antibody that causes agglutination of a specific antigen
References in periodicals archive ?
Delayed immune hemolysis due to rapid isohemagglutinin production by donor-derived lymphocytes has been reported in transplants with a minor or bidirectional ABO-mismatched graft and is known as passenger lymphocyte syndrome [6-10].
Mielcarek and colleagues [20] observed a significantly earlier disappearance of isohemagglutinin titers in recipients of matched unrelated-donor grafts compared with recipients of matched related-donor grafts.
Recipients of major ABO-incompatible stem cell grafts possess isohemagglutinins directed against donor RBCs and are at risk for immediate or delayed hemolysis of donor RBCs and destruction of donor erythroid precursor cells, causing delayed erythroid engraftment and pure red cell aplasia (PRCA).