isoniazid


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Related to isoniazid: Pyrazinamide

i·so·ni·a·zid

 (ī′sə-nī′ə-zĭd)
n.
A crystalline antibacterial compound, C6H7N3O, used in the treatment of tuberculosis.

[isoni(cotinic acid), isomer of nicotinic acid (iso- + nicotinic acid) + (hydr)azid(e), one of its constituents (hydr(o)- + az(o)- + -ide).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

isoniazid

(ˌaɪsəʊˈnaɪəzɪd) or

isoniazide

n
(Pharmacology) a soluble colourless crystalline compound used to treat tuberculosis. Formula: C6H7N3O
[C20 isoni(cotinic acid hydr)azid(e)]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

i•so•ni•a•zid

(ˌaɪ səˈnaɪ ə zɪd)

n.
a water-soluble solid, C6H7N3O, used in the treatment of tuberculosis.
[1950–55; short for isonicotinic acid hydrazide]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.isoniazid - antibacterial drug (trade name Nydrazid) used to treat tuberculosis
antibacterial, antibacterial drug, bactericide - any drug that destroys bacteria or inhibits their growth
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

isoniazid (INH)

n isoniazida
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
They found that while all three drugs significantly altered the composition of the mice's gut microbiome, but mice treated with isoniazid combined with pyrazinamide showed an increase in susceptibility to Mtb infection.
Each patient received a daily total dose of rifampicin (600 mg), isoniazid (300 mg) pyrazinamide (1600 mg) and ethambutol (1100 mg) for two months (intensive phase), followed by rifampicin (600 mg) plus isoniazid (300 mg) for four months (continuation phase).
The most common medication used was isoniazid (730/752, 97.1%), followed by rifampin (20/752, 2.7%); 2 children whose index patient had MDR TB received ethambutol and pyrazinamide.
Keywords: Drug Metal Complexes, Isoniazid, Scanning Electron Microscopy, X-Ray Diffraction and Cytotoxicity.
Isoniazid was marketed in mid of 1950,s and Rifampicin in 1970,s.
The first regimen comprises 9 months of isoniazid treatment.
tuberculosis from patients who subsequently had a relapse or were cured to determine the MIC values of isoniazid and rifampin that were below the standard resistance breakpoint.
A bactericidal agent used with suicidal intent: isoniazid. Journal of the Child 2014; 14: 78-80.
A large randomized clinical trial of 3HP administered by DOT, which included children aged 2-17 years, demonstrated that 3HP was as well-tolerated and as effective as 9 months of daily isoniazid (9H) for preventing TB (5).
Study participants were randomly assigned to a one-month course of rifapentine and Isoniazid or a nine-month course of Isoniazid.