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Related to isotype: idiotype, allotype


1. A biological specimen or other element that is a duplicate of the holotype.
2. Any of several classes or subclasses of immunoglobulins, such as immunoglobulins A and G, that are distinguished by differences in the amino acid sequence of the constant regions of their heavy chains. All isotypes are usually found in every individual of a species.

i′so·typ′ic (-tĭp′ĭk) adj.
i′so·ty′py (-tī′pē) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


the presentation of statistical information in a row of diagrams using the international picture language created by Otto Neurath (1882–1945)
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈaɪ səˌtaɪp)

1. one of two or more separate biological populations of the same or a similar type.
2. any epitope that is common to all individuals in a species.
i`so•typ′ic (-ˈtɪp ɪk) adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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It also underscores the concrete possibility of fine-tuning the PPAR isotype activity through appropriate treatments in order to improve overall performance and health of dairy cattle.
The present treatment is based on herbarium specimens, including an isotype and two other collections of V.
Through cross-sectional modeling, the researchers found that risk factors associated with progressive MGUS were immunoglobulin A isotype, a monoclonal spike of 15 g/L or more, a skewed (<0.1 or >10) serum free light chains ratio, and severe immunoparesis (at least two suppressed uninvolved immunoglobulins; adjusted odds ratios, 1.80, 23.5, 46.4, and 19.1, respectively).
According to the company, the RF IgM has been reported to be the main RF isotype in confirmed RA patients with a prevalence of 70-80%.
Sections of 5 [micro]m were cut and stained initially with haematoxylin and eosin and then with an ED1 (homologous to human CD68), ED2 (homologous to human CD163), or isotype control antibody [32].
Anti-human fluorochrome-conjugated CD117/ c-kit (clone 104D2), FceRI (clone CRA-1), and CD31 (clone WM59), and their isotype controls, Ms IgG1 (clone MOPC-21) and Ms IgG2b (clone MPC-11), were purchased from BioLegend (San Diego, CA).
Furthermore, a pronounced negative association of anti-dsDNA IgM isotype with LN (p = 0.005) was demonstrated.
Lastly, the results showed that the anti-FMDV IgG1 was the predominant isotype in all vaccinated animals given that there was a minor difference between total IgG and IgG1, and low levels of specific FMDV IgG2 were detected in [B.sub.2]T and [B.sub.4]T groups with average antibody titres of 1.1 [+ or -] 0.3 and 1.9 [+ or -] 0.7, respectively (data not shown).