MIC endpoints were determined for nine antifungal agents: micafungin, caspofungin, flucytosine, posaconazole, voriconazole, itraconazole
, fluconazole, anidulafungin and amphotericin B.
In terms of the brand programs, the Company continues to progress the commercialisation of its patented formulation of itraconazole
for the treatment of certain fungal conditions and as a potential treatment for certain cancers.
Following the corporate name change, INHIBITOR will launch a new website (http://www.inhibitortx.com) to showcase INHIBITOR's vision and development strategy for SUBA-Itraconazole, a proprietary formulation of the FDA approved anti-fungal drug itraconazole
designed to enable improved bioavailability compared to conventional itraconazole
when used as an anti-cancer treatment, as well as novel compounds that inhibit upstream targets of the Hedgehog Pathway as treatments for cancer and non-cancerous proliferation disorders.
Pulmatrix and Cipla Technologies, a subsidiary of Cipla Limited announced their entry into a Definitive Agreement for the co-development and commercialization of Pulmazole, an inhaled iSPERSE formulation of the anti-fungal drug itraconazole
for the treatment of allergic bronchopulmonary aspergillosis in patients with asthma.
CHICAGO -- Oral itraconazole
shows potential for treatment of locally advanced or metastatic basal cell carcinoma (BCC) as well as Gorlin syndrome, Justin J.
The patient progressed with favorable clinical recovery after five weeks, when treatment was switched to Itraconazole
. This case illustrates an exuberant form of disseminated histoplasmosis.
A 44-year-old African American man presented with a past medical history of pulmonary sporotrichosis treated with itraconazole
in 2008 and in 2011 for 5 months at least and with a documented negative sputum culture thereafter.
Fluconazole was switched to itraconazole
for better bone penetration.
Objective: To compare the efficacy of single dose of oral itraconazole
400mg with 1% topical clotrimazole in the treatment of pityriasis versicolor.
This study examined the delivery of the antifungal drugs itraconazole
, voriconazole, and terbinafine to Japanese quail (Coturnix japonica) via an impregnated implant.
The mycological literature devotes much attention to the issue of fungal resistance and reduced susceptibility to commonly used antifungal drugs [8-13], and it emphasizes that the process is still in progress, especially for azole chemotherapeutics (ketoconazole, tioconazole, miconazole, fluconazole, itraconazole