Also found in: Thesaurus, Medical, Idioms, Encyclopedia.
1. Very excited or agitated, especially from taking a stimulant.
2. Having well-developed muscles.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.