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A type of leishmaniasis occurring chiefly in India, caused by the protozoan parasite Leishmania donovani and characterized by fever, enlargement of the spleen and liver, progressive anemia and leukopenia, and weight loss.

[Urdu kālā āzār : kālā, black (from Sanskrit kāla-; see Kali) + āzār, disease (from Persian, from Middle Persian, pain, torment, from āzārdan, āzār-, to torment : ā-, to + -zār-, to make angry).]


(Pathology) a tropical infectious disease caused by the protozoan Leishmania donovani in the liver, spleen, etc, characterized by fever and weight loss; visceral leishmaniasis
[from Assamese kālā black + āzār disease]


(ˌkɑ lə əˈzɑr)

a tropical parasitic disease marked by irregular fevers, enlarged spleen, and anemia, caused by the protozoan Leishmania donovani, and transmitted by sand flies.
[1880–85; < Hindi, =kālā black + Persian āzār disease]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.kala-azar - leishmaniasis of the viscerakala-azar - leishmaniasis of the viscera  
kala azar, leishmaniasis, leishmaniosis - sores resulting from a tropical infection by protozoa of the genus Leishmania which are spread by sandflies
References in periodicals archive ?
Kala-azar occurs in more than 80 countries in Asia, Africa, Southern Europe and South America with a total of 200 million people at risk (Murray H W, (1) & Guerin P et al.
Kala-azar is endemic in remote areas of northern Jonglei and southern Upper Nile states where communities are exposed to insect bites as they often sleep without mosquito nets, the report noted.
Relationship between sand fly fauna and kala-azar endemicity in Bangladesh.
Persons reported with fever for >2 weeks, anemia, weight loss, and palpable spleen or liver and who were negative for malaria were tested for kala-azar by using the rK39 diagnostic kit (InBiOS, Seattle, WA, USA).
These were clinically diagnosed as kala-azar cases and confirmed by one or multiple methods such as bone marrow or spleen aspiration microscopic examination, rk-39 strip test, indirect fluorescent antibody test (IFAT > 1/128 accepted as positive result) and KAtex serological tests and PCR, with bone marrow aspiration and IFAT being the most frequently used.
The natural history of Sudanese post kala-azar dermal leishmaniasis: Clinical, immunological, and prognostic features.
Kala-azar caused by Leishmania donovani is a common endemic infection in eastern India which commonly presents with fever, anaemia, weight loss, darkening of skin and hepatosplenomegaly.
A cluster of cases of severe cardiotoxicity among kala-azar patients treated with a high-osmolarity lot of Sodium Antimony Gluconate.
Nasdaq: GILD) announced today that it will donate 445,000 vials of AmBisome(R) (amphotericin B liposome for injection) over five years to help the World Health Organization (WHO) treat more than 50,000 patients with visceral leishmaniasis (VL), also known as kala-azar.
They also pointed out that kala-azar existed in the valleys of river Indus and Shyok for a long time and elderly inhabitants of the area recalled the disease coming in waves and causing many deaths in children.
Pradeep Das, Director, Rajendra Memorial Research Institute of Medical Sciences, Patna, Participated in the Informal Consultations on Epidemiological Information on Disease Burden due to Kala-azar, at Thimpu (March 8-10,2011).
Patient did not have any history of kala-azar or previous nodular or ulcerated lesions.