kallikrein


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kallikrein

(ˌkælɪˈkriːɪn; kəˈlɪkriːɪn)
n
(Biochemistry) a type of protease that liberates kinins from kininogens
Translations

kal·li·kre·in

n. calicreína, enzima potente de acción vasodilatadora.
References in periodicals archive ?
Skin kallikreins are expressed in the outer layer of the human skin and represent an attractive target.
KVD900 is the second clinical candidate from a portfolio of oral plasma kallikrein inhibitors for potential treatment of HAE.
In affected patients, "activation of the kallikreinkinin cascade leads to uncontrolled generation of plasma kallikrein and consequent proteolysis of high-molecular-weight kininogen.
Elevated miR-375 Expression in HNSCC Cells Regulates Kallikrein 6, Kallikrein 10, and MMP-9 mRNA Expression
Work in the Feener lab had previously implicated plasma kallikrein in diabetic eye complications.
Levels of glandular kallikrein in whole saliva obtained from patients with solid tumors remote from the oral cavity.
We hypothesise that her intraoperative deterioration resulted from acute elevation of kallikrein released during surgical manipulation of the tumour.
We previously reported that inhalation challenge with a variety of noxious agents results in increased tissue kallikrein activity and subsequent kinin generation in the airways.
DX-88, a specific and potent kallikrein inhibitor discovered at Dyax, is being developed for the treatment of HAE in a joint venture between Dyax Corp.
This article will discuss the biochemistry of PSA (human glandular kallikrein 3, or hK3) and its molecular forms, and human glandular kallikrein 2 (hK2), another member of the human kallikrein gene family.
The two proteins are encoded by alternative mRNA splice variants of the genes for prostate- specific antigen (PSA) and a related protein, human kallikrein 2 (hK2).