"If you suffer, chances are it could be hereditary but can also be caused by other factors such as bad tissue nutrition, poor keratinization
and trauma from an overzealous manicure," she told the Mail.
Dyskeratosis is characterized by individual cells showing abnormal cell maturation often with abnormal keratinization
in the deeper layers of the epidermis.
Additionally, a complementary technique the company has developed also supports late-phase wound healing events known as re-epithelialization and keratinization
Nuclear and cellular pleomorphism is minimal as compare to the moderately differentiated tumours where there is less keratinization
and more nuclear to cellular pleomorphism.
(7) This abnormal structure of the skin results from extreme keratinization
. (5) The skin that becomes rigid because of extreme keratinization
(10-fold thicker than the normal) makes movement difficult, and thereby deep fissures occur on this non-elastic skin.
Disorders of keratinization
. In: Burns T, Breathnach S, Cox N, Griffiths C, editors.
The bizarre, rapid proliferation, and immature keratinization
produce the distinctive feature of porokeratosis (coronoid lamella) [Figure 2].
Symblepharon, i.e., adhesion from the edges of the two eyelids (white arrow) and keratinization
of the sclerocorneal limbus (yellow arrow) in the right eye.
Tissue growth is accompanied by a differentiation, the outcomes of which is physical changes such as papillary development and increased keratinization
(Tamate et al., 1962).
Occasionally, individual epidermoid cells possessed lamellar cytoplasmic keratinization
or larger compact lamellations of keratin (keratin pearls) [Figure 1]c.
Histopathologically, multilobulated tumors characterized by atypical squamous cells, cystic areas, widespread trichilemmal keratinization
, and extensive necrosis were seen [Figure 5].
Based on presence of well circumscribed but unencapsulated dermal nodule comprising of cystic structures of variable sizes and presence of abrupt keratinization
in these horn cysts, it was diagnosed as Trichoepithellioma (Fig.