Moderate complications may include infection, pigmentary alteration, anesthesia toxicity, and eruptive keratoacanthomas
, while severe complications may include hypertrophic scarring, ectropion formation, and disseminated infection.
Previously described rash/skin lesions (keratoacanthomas
, SCC, hyperkeratosis) associated with transforming growth factor-ss (TGF-ss) inhibiting therapies have also been observed.
Pseudo-epitheliomatous lesions can mimic squamous cell carcinoma and keratoacanthomas
associated with immunosuppressive therapy in a patient with systemic lupus erythematosus.
Frank, "Detection of human papillomavirus DNA in keratoacanthomas
by polymerase chain reaction," American Journal of Dermatopathology, vol.
During a comprehensive survey of a number of invasive and noninvasive skin lesions , we observed that C4.4A was only upregulated in the front of invasive lesions, and this occurred independently of whether they were malignant (squamous cell carcinomas) or benign (keratoacanthomas
Two of the previous reports showed SCC with HS and DD: one in the groin [sup] and the other in the perianal region.[sup] Another report described multiple keratoacanthomas
with AI and DDD.[sup] However, it is unclear whether DDD itself could increase the risk of SCC independently of AI.
A biopsy was performed with the differential diagnosis of DLE, vitiligo, lupus vulgaris, hypopigmented lesions of tuberculoid leprosy, actinic keratoses, coral reef keratoacanthomas
. Histopathological examination confirmed the diagnosis of DLE (Figure 3).
The differential diagnosis for PN includes dermatitis herpetiformis, scabies, lichen simplex chronicus, hypertrophic lichen planus, perforating disorders, atopic dermatitis, allergic contact dermatitis, neurotic excoriations, and multiple keratoacanthomas
Muir-Torre syndrome is an autosomal-dominant disease associated with multiple keratoacanthomas
and visceral malignancies, especially genitourinary and gastrointestinal.
a very painful condition that may require extensive surgery of the distal phalanx may be associated with foreign body injuries such as steel wool particles.
Side effects Frequency (%) Arthralgia 54% Nausea 34% Skin erythema 28% Vomiting 14% Headache 13% Fatigue 11% Keratoacanthomas
2% Hypertransaminasemia 2% Alopecia 1% QTc prolongation 1%