Multiple myeloma in a patient with systemic lupus erythematosus, myasthenia gravis and non-familial diffuse palmoplantar keratoderma
Diffuse non-epidermolytic palmoplantar keratoderma
(NEPPK) is a rare condition in which individuals have thickened, yellowish skin over their palms and soles, thickened nails and suffer from excessive sweating.
Carcinoma cuniculatum arising in focal plantar keratoderma
The team of scientists from A*STAR's Institute of Medical Biology (IMB), in collaboration with hospitals and research centres from the UK, Japan and Tunisia, found that this skin disorder, called punctate palmoplantar keratoderma
(punctate PPK), is caused by mutations in the AAGAB gene.
Dermatolojik muayenede yuz, boyun ve ekstremitelerde daha belirgin olan hipo ve hiperpigmente makullerin olusturdugu retikuler diskromik poikiloderma (Resim 1), govde, ekstremite ve el-ayak dorsal yuzlerinde atrofi, el parmaklari arasinda proksimal perdelenme, el-ayak basparmak tirnaklarinda subungal hiperkeratoz ve sari renk degisikligi, diffuz palmoplantar keratoderma
ve fleksiyon kontrakturu saptandi (Resim 2).
Mucocutaneous manifestations include the presence of circinate balanitis and keratoderma
Ofuji'nin papuloeritrodermast olgularinda kasinti (%100), lenfadenopati (%54), eozinofili (%84), serum IgE yuksekligi (%65), lenfopeni (%41), palmoplantar keratoderma
(%35), tirnak yatagi degisiklikleri (%8) ve trombositopeni (%4) gorulebilmektedir (18).
Plakoglobin: Earlier mutations in plakoglobin were reported in a variant of ARVC called Naxos disease, which is characterized by signature features of ARVC accompanied by diffuse non-epidermolytic palmoplantar keratoderma
(NEPPK) and wooly hair (WH) (56), a recently identified novel autosomal dominant plakoglobin mutation without any cutaneous and hair abnormalities.
of the Papillon-Lefevre type associated with diffuse hyperkeratosis follicularis.
Calluses visually identified as resulting from physical labor and hereditary keratoderma
or Darier's disease, identified by visual inspection and family history, were excluded.
Salvax[TM] Duo is available by prescription only and both Salvax[TM] Foam and Hydro 40[R] Foam are indicated for hyperkeratotic conditions such as dermatitis, psoriasis, xerosis, ichthyosis, eczema, keratosis, keratoderma
and dry, rough skin, as well as corns and calluses.
Burada primer comak parmagin eslik ettigi bir herediter palmoplantar keratoderma
olgusunu nadir rastlanmasi nedeniyle sunuyoruz.