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Related to keratohyalin: trichohyalin
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Noun1.keratohyalin - hyaline in the large granules of the stratum granulosum
hyalin, hyaline - a glassy translucent substance that occurs in hyaline cartilage or in certain skin conditions
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References in periodicals archive ?
Koilocytes containing enlarged and irregular nuclei, perinuclear halos, and coarse keratohyalin granules may be found in the granular and upper spinous layers.
The granular layer is composed of keratinocytes with an array of filaggrin-rich keratohyalin granules and lamellar granules packed with lipid bilayers.
Electron microscopy reveals abnormal keratohyalin granules with poorly formed intracellular lipid lamellae in the stratum coneum.1 Prenatal diagnosis with chorionic villus sampling (CVS) and amniotic fluid cells analysis is advised in women with previous affected baby.
Through the process of terminal differentiation, SG KCs produce two membrane-circumscribed granules, keratohyalin granules and lamellar bodies.
While papillary structures with hyperkeratosis and hypergranulosis are intensely observed in laryngeal verruca vulgaris, there are no significant granular cells and keratohyalin granules in verrucous carcinoma.
Similar to classic BD, pagetoid BD always shows full-level involvement of the epidermis, scattered multinucleated tumor giant cells, keratohyalin granules, single-cell keratinization, and intercellular bridges visible between pagetoid cells, while EMPD lesion contains pagetoid cells well demarcated from nearby epidermal cells, flattened basal layer, stratum corneum involved, acinar structures, and no intercellular bridge.
In epidermis, moderate to severe acanthosis, mild to severe hyperkeratosis, hydropic degeneration of keratinocytes and many koilocytes with variably sized keratohyalin granules were observed.
In 2006, Irvine and McLean (7) studied the histology of normal and atopic skin and demonstrated that the skin in AD has a defective barrier, with an absence of filaggrin-containing keratohyalin granules in the epidermal granular layer.