keratohyalin


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Related to keratohyalin: trichohyalin
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Noun1.keratohyalin - hyaline in the large granules of the stratum granulosum
hyalin, hyaline - a glassy translucent substance that occurs in hyaline cartilage or in certain skin conditions
References in periodicals archive ?
Similar to classic BD, pagetoid BD always shows full-level involvement of the epidermis, scattered multinucleated tumor giant cells, keratohyalin granules, single-cell keratinization, and intercellular bridges visible between pagetoid cells, while EMPD lesion contains pagetoid cells well demarcated from nearby epidermal cells, flattened basal layer, stratum corneum involved, acinar structures, and no intercellular bridge.
In 2006, Irvine and McLean (7) studied the histology of normal and atopic skin and demonstrated that the skin in AD has a defective barrier, with an absence of filaggrin-containing keratohyalin granules in the epidermal granular layer.
The granular layer was thickened and showed coarse keratohyalin granules with marked vacuolization of the granular and upper spinous layers.
On the other hand, a keratohyalin layer and dry flaky keratin, as would be seen in an epidermoid cyst, are also absent.
Within the granular layer, comeocytes produce keratohyalin granules, which expel their lipid contents into the intra-cellular spaces.