The high level of glucose in the blood of lambs from the traditional, traditional pelleted and TMR3 may be caused by altering the metabolic process including decreased use of glucose with increased oxidation of butyrate and ketogenesis
(Giesecke et al.
This gene also plays a significant role in ketogenesis
in the sheep rumen epithelium during development, and is up-regulated in the rumen epithelium of EW Holstein calves and Japanese Black male calves [29,16] Augmented production of VFAs influenced by the intake of solid feed during weaning may encourage ketogenesis
in cattle rumen epithelial cells by the activation of HMGCS2 and peroxisome proliferator-activated receptor alpha to encourage papillary growth .
Cunnane reported interim results of an investigation of induced ketogenesis
in patients with mild cognitive impairment (MCI).
Reagent strips for urinalysis are available over the counter and allow for easy tracking of one's status in ketogenesis
by indicating the ketone level in the urine.
Impact of pre-exercise rapid-acting insulin reductions on ketogenesis
following running in Type 1 diabetes.
Metabolic acidosis is a key feature due to the production of lactic and glutaric acids, and hypoketotic hypoglycemia due to impaired [beta]-oxidation and ketogenesis
Arsenic also altered the lipid metabolic product profile in a pattern that suggests disruption in the tricarboxylic acid (TCA) cycle and increased ketogenesis
(Ditzel et al.
In the diabetic control, elevated level of transaminase that is active in the absence of insulin because of the availability of amino acids in the blood stream is responsible for the high rate of gluconeogenesis and ketogenesis
metabolism (Rui 2014).
Starvation causes the hepatic glycogen stores to deplete and ketogenesis
to take place in the liver, decreased insulin sensitivity and increased production of counterregulatory hormones such as glucagon, cortisol, and epinephrine.
In ketosis oxaloacetate level is decrease in metabolism and not sufficient acetyl-CoA (co-enzyme A) produce in TCA cycle or ultimately ketogenesis
(Krebs et al.
Hue, "Comparison of the effects of various amino acids on glycogen synthesis, lipogenesis and ketogenesis
in isolated rat hepatocytes," The Biochemical Journal, vol.
In addition to FFA, growth factors such as insulin growth factors 1 and 2 (IGF1 and IGF2) and fibroblast growth factor 21 (FGF21), a secreted protein from liver, involved in the control of glucose homeostasis, insulin sensitivity, and ketogenesis
were recently found to induce the expression of genes encoding mitochondrial UCP2, UCP3, and superoxide dismutase-2 (SOD2) involved in antioxidative pathways in cardiomyocytes in culture preventing inflammation and hypertrophic process .