Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.


 (kī′nās′, -nāz′, kĭn′ās′, -āz′)
Any of various enzymes that catalyze the transfer of a phosphate group from a donor, such as ADP or ATP, to an acceptor protein. Kinases regulate many essential cellular processes.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˈkaɪneɪz; ˈkɪn-)
1. (Biochemistry) any enzyme that can convert an inactive zymogen to the corresponding enzyme
2. (Biochemistry) any enzyme that brings about the phosphorylation of a molecule
[C20: from kin(etic) + -ase]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈkaɪ neɪs, -neɪz, ˈkɪn eɪs, -eɪz)

an enzyme that effects the transfer of a phosphate group from ATP to another molecule.
[1900–05; kin (etic) + -ase]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.kinase - an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
This report on the tyrosine kinase inhibitors market analyzes the current and future scenario of the global market.
Summary: This report on the tyrosine kinase inhibitors market analyzes the current and future scenario of the global market.
The firm has also received accelerated approval for the product to treat adult and paediatric patients 12 years of age and older with solid tumours, which have a neurotrophic tyrosine receptor kinase gene fusion without a known acquired resistance mutation.
The combination of RBC and ProQinase will create a leading kinase drug discovery company, with a diverse offering and operations in Europe and the United States.
This includes inactive receptor kinase, LRR-receptor kinase, serine/ threonine-protein kinase, LRR-F-box containing protein and powdery mildew resistance protein 5 (PMR 5).
Pfizer announced results from its Phase 2a study of PF-06651600, an oral Janus kinase 3 inhibitor, and PF-06700841, a tyrosine kinase 2/JAK1 inhibitor, compared to placebo, in patients with moderate to severe alopecia areata, an autoimmune disease characterized by hair loss and often associated with profound psychological consequences.
The experimental models were given standard cooling therapy (therapeutic hypothermia) alone and in combination with a selective Src kinase inhibitor, PP2, that blocks a regulatory enzyme of apoptosis (cell death), which intensifies as a result of hypoxia-ischemia.
Chromosomal microdeletions and duplications are one of the major causes of congenital malformations and developmental delay.Lately by the effect of array-CGH,many new syndromes are defined in patients with congenital malformations and developmental delay.Xp21 contiguous gene deletion syndrome is one of the rare microdeletion syndromes.This syndrome is characterized by developmental delay,congenital adrenal hypoplasia, DuchenneMuscularDystrophy (DMD) and glycerol kinase deficiency.
Lurie Children's Hospital of Chicago found that these tumours' growth and tendency to metastasize are regulated by a protein kinase called Polo-like kinase 4 (PLK4), which is increased in AT/RT.
Firstly, high level of PIM-1 kinase was discovered in lymphoma tumours and leukaemia [3].