kinesin


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ki·ne·sin

 (kə-nē′sĭn)
n.
Any of a group of motor proteins that move along microtubules and are involved in cell division and the transport of cytoplasmic organelles.

References in periodicals archive ?
This self-propelling fluid, which the authors of the study say holds promise for the creation of an entirely new class of fluids that can flow without any mechanical effort, was developed using filaments called microtubules and tiny molecular motors called kinesin.
Global Markets Direct's, 'Kinesin Spindle Protein (KSP or Eg5) - Pipeline Review, H1 2016', provides in depth analysis on Kinesin Spindle Protein (KSP or Eg5) targeted pipeline therapeutics.
These complexes are 1) centralspindlin, consisting of the mitotic kinesin MKLP1 (also known as kinesin 6) and the Rho family GAP CYK-4 (also known as MgcRacGAP); and 2) the chromosomal passenger complex (CPC), consisting of the Aurora B kinase and three additional proteins involved in its localization and activation: INCENP, Survivin, and Borealin.
Creation of the neural structure, unachievable by normal manufacturing techniques, begins by altering the behavior of kinesin motor proteins -- biological machines found in every human cell.
RNA-binding proteins (RBPs), kinesin motor proteins, mRNAs and noncoding RNAs (ncRNAs) are involved in dendritic mRNA transport and translational regulation.
5 August 2014 - US personalised medicine specialist Caris Life Sciences unveiled Tuesday data from a case study showing that its Caris Molecular Intelligence tumour profiling service helped guide successful therapy with both a kinesin 11 (KIF11) inhibitor and imatinib for a patient with neuroendocrine carcinoma with an activating KIT mutation.
The Company's pipeline includes ARQ 087, designed to inhibit fibroblast growth factor receptor, ARQ 621, designed to inhibit the Eg5 kinesin motor protein, and ARQ 736, designed to inhibit the RAF kinases.
The German company said that this first-in-man Phase I, open label, dose escalation trial will investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of orally administered 4SC-205, which is an oral Eg5 kinesin spindle protein inhibitor.
Specific topics include molecular dynamics simulation studies of couples protein and water dynamics, heat transfer in nanostructures, energy flow pathways in photoreceptor proteins, and the chemo-mechanical coupling mechanisms of kinesin and dynein.
The strategic alliance, initiated in June 2001, included a minimum five year research term, which has generated two drug candidates that inhibit kinesin spindle protein (KSP), ispinesib and SB-743921, and a potential drug candidate, GSK-923295, which targets CENP-E.
Located within dendrites and axonal projections, microtubules serve as tracks for the transportation of post-Golgi vesicles by microtubule bound motor proteins (such as kinesin and dynein).
Within living calls, a two-headed protein called kinesin acts as a biological motor, hauling cargo.