kinetochore


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Related to kinetochore: centrosome

ki·net·o·chore

 (kə-nĕt′ə-kôr′, -nē′tə-, kī-)
n.
Either of two submicroscopic attachment points for chromosomal microtubules, present on each centromere during the process of cell division.

[kineto- + Greek khōros, place; see -chore.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

kinetochore

(kɪˈnɛtəˌkɔː; kɪˈniːtəˌkɔː; kaɪˈnɛtəˌkɔː; kaɪˈniːtəˌkɔː)
n
(Genetics) a centromere, a protein structure found in chromosomes
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ki•ne•to•chore

(kɪˈni təˌkɔr, -ˌkoʊr, -ˈnɛt ə-, kaɪ-)

n.
a structure on the chromosome, at or near the centromere, to which spindle fibers attach during cell division.
[1930–35; < Greek kīnetó(s)]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.kinetochore - a specialized condensed region of each chromosome that appears during mitosis where the chromatids are held together to form an X shape; "the centromere is difficult to sequence"
anatomical structure, bodily structure, body structure, complex body part, structure - a particular complex anatomical part of a living thing; "he has good bone structure"
chromosome - a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order; "humans have 22 chromosome pairs plus two sex chromosomes"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Afterward, the kinetochore reappears, the microtubules pull homologous genetic material and pair with meiotic spindles in the metaphase-I (M-I) (Grondahl, 2008).
Chromosome congression in the absence of kinetochore fibres.
The CENPF gene plays a role in attaching the kinetochore and spindle microtubules [29].
(16.) Drew Berry, "Chromosome and Kinetochore," WEHl.tv (2013), https://www.wehi.edu.au/wehi-tv/chromosomeand-kinetochore (accessed 29 July 2017).
It is known that kinetochore is the attachment site of spindle microtubules in the centromeric region of a chromosome [9, 10].
Lin, "Prediction of midbody, centrosome and kinetochore proteins based on gene ontology information," Biochemical and Biophysical Research Communications, vol.
Additionally, TTK activity at the kinetochore stimulates MAD1-dependent conformational changes in MAD2L1 from an open to a closed form [21, 22], which is crucial for inhibition of anaphase-promoting complex/cyclosome (APC/C) [6, 23-26], the ubiquitin ligase that controls anaphase onset.
The most represented GO term was the condensed chromosome kinetochore (-[log.sub.10] (p value) = 13.0822) in the cellular component category.
Centromeric RNAs are closely associated with centromeric chromatin and kinetochore formation.
Prior to anaphase, the CPC is highly enriched at the inner centromere, and ABK activity contributes to spindle and kinetochore assembly, spindle assembly checkpoint signaling, and error correction (Tanaka et al., 2002; Emanuele et al., 2008; Lampson and Cheeseman, 2011; Moutinho-Pereira et al., 2013).