This is also the first reported case of a reversal of a loss of labyrinthine CISS (constructive interference in a steady state) signal, suggesting that T2-weighted hyposignal may be attributable to an alteration in labyrinthine fluid
content and not to fibrosis only.
* 1 was a unique human study in which intratympanic ciprofloxacin drops were instilled into the middle ear space of 10 patients with an acoustic neuroma; the authors found no evidence of measurable absorption of the drug in the labyrinthine fluid
, cerebrospinal fluid, or serum, which indicates that the chance of ciprofloxacin toxicity is low.
(6) After the Gelfoam was removed, they irrigated the middle ear with saline and aspirated the labyrinthine fluid
by puncturing the RWM with a glass capillary pipette.
Effects of hyperosmolar solutions on the labyrinthine fluid
Clinical implications of experiments on alteration of the labyrinthine fluid