beta-lactamase

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be·ta-lac·ta·mase

 (bā′tə-lăk′tə-mās′, -māz′, bē′-)
n.
Any of various enzymes that hydrolyze and inactivate beta-lactam antibiotics such as penicillin, found in many antibiotic-resistant bacteria.

[beta-lactam, cyclic amide occurring in penicillins (beta + lact(one) + am(ide)) + -ase.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.beta-lactamase - enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Translations

be·ta-lac·ta·mase

a. beta-lactamasa, enzima que destruye el conjunto de beta-lactam antibióticos penicílicos haciéndolos no efectivos;
beta-lactamase resistanceresistencia de beta-lactamasa, a algunos tipos de penicilina.
References in periodicals archive ?
Lactamase producing bacteria are increasing in number and inflicting additional severe infections, as a result of their continuous mutation (Bora et al., 2014).
The ability of an organism to produce a [beta]eta lactamase may be chromosomal and constitutive or a plasmid-associated acquired property.
The attachment of beta lactamase to the antibiotic is prevented by oxyimino group (Kangh et al., 2005; Sachin et al., 2011).
Prevalence of extended spectrum [beta] lactamase producing Enterobacteriaceae in humans living in municipalities with high and low broiler density.
Prevalence of extended spectrum beta lactamase producing Escherichia coli and Klebsiella pneumoniae urinary isolates in a tertiary care hospital in Kathmandu, Nepal.
Extended-spectrum beta lactamase (ESBL) producing Enterobacteriaceae are major agents of nosocomial and community acquired infections.
The main objective of study is to determine the frequency of ESBLs and Amp C beta lactamase producing Escherichia coli and Klebsiella pneumonia isolated from neonatal sepsis in a tertiary care hospital Lahore.
Table-III: Frequency of various interventions among the AmpC b lactamase harbouring neonates.
Frequency of Extended Spectrum Beta Lactamase Producing Enterobacteriaceae Among Urinary Pathogen Isolates.
These enzymes were at first given the designation IRT for inhibitor-resistant TEM beta lactamase; however, all have subsequently been renamed with numerical TEM designations.
Antibiotic resistance was determined by agar disc diffusion method using Mueller-Hinton agar according to Clinical and Laboratory Standards Institute recommendations and the production of b- lactamase was detected with the iodometric slide test.