A common finding in patients with CVID is the conspicuous paucity or absence of plasma cells in the lamina propria
of the gastrointestinal tract, which is usually confirmed with negative immunohistochemistry staining for CD138, a marker for plasma cells (Figure 2, A and B).
The number of the eosinophils per one high-power field (HPF) in lamina propria
Aim of this study was to determine the role of preoperative NLR and RDW in predicting lamina propria
invasion in bladder cancer.
were among mucosal epithelial cells, often near the basement membrane and rarely within the lamina propria
(Figure 1, panel B; online Technical Appendix) and not present in other organs.
The intestinal glands were greatly developed in the ileum, lymphoid nodules were observed in the mucosa, and diffuse lymphoid tissue was distributed in the lamina propria
. Meanwhile, goblet cells gradually increased from the duodenum to the ileum.
Increased permeability of microvascular capillaries in the lamina propria
results in RE because of accumulation of extracellular matrix in the Reinke's space (1).
Histopathological examination revealed a dense homogenous eosinophillic material in the lamina propria
showing positive orange-red staining with Congo-red with apple-green birefringence under polarized light (Figure 1).
IL-21R immunopositive (IL-21[R.sup.+]) cells were semiquantitatively scored as follows: The mucosa-associated lymphoid compartments were individually scored: mucosa (M): intraepithelial lymphocyte (IEL) compartment (surface epithelium), lamina propria
, and follicle-associated epithelium (FAE); submucosa (SM): isolated (solitary) lymphoid follicles (ILF), Peyer's patches (ileum)/colonic IEL (colon), and isolated infiltrating lymphocytes; and muscularis externa (ME): IELs and isolated infiltrating lymphocytes.
Microscopically polypoid ganglioneuromas can appear as collections of spindle cells in a fibrillary matrix, irregular groups, and nests of ganglion cells in the lamina propria
. They can also appear as a nodular mucosal and submucosal ganglion and spindle cell proliferation that suggests a neurofibroma or as nodular mucosal proliferations of clustered ganglion cells admixed with varying amounts of spindle cells without any significant disarray of the mucosal architecture .
The mucosa consisted of 3 layers, including the epithelium, lamina propria
, and muscularis mucosae, and is organized into villi.
In regard to subepithelial/lamina propria fibrosis (FB), this finding was only evaluable if patient samples contained lamina propria
in their biopsy and 57 (85%) in EoE-D and 54 (80%) in EoE- AP were evaluable and fibrosis was observed numerically more in EoE-D but was not significant.
The WHO criteria (1978) for histopathological diagnosis of OLP include thickened ortho- or parakeratinised epithelium, liquefaction degeneration of basal layer, well-defined juxtaepithelial lymphocytic infiltration, and Civatte bodies in basal epithelium and lamina propria