lamivudine


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la·miv·u·dine

 (lə-mīv′yo͞o-dēn′)
n.
An antiviral drug, C8H11N3O3S, that is a nucleoside reverse transcriptase inhibitor and is used in the treatment of chronic hepatitis B and, in combination with other drugs, in the treatment of HIV infection.

[Probably (methy)l + ami(no)- + -vudine, antiviral suff. (from zidovudine).]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.lamivudine - a nucleoside reverse transcriptase inhibitor that is very effective in combination with zidovudine in treating AIDS and HIVlamivudine - a nucleoside reverse transcriptase inhibitor that is very effective in combination with zidovudine in treating AIDS and HIV
NRTI, nucleoside reverse transcriptase inhibitor - an antiviral drug used against HIV; is incorporated into the DNA of the virus and stops the building process; results in incomplete DNA that cannot create a new virus; often used in combination with other drugs
Translations

lamivudine

n lamivudina
References in periodicals archive ?
Tenders are invited for Procurement of drugs Glucosaimine 500mg Tab, Glucosamine 250 mg + Chondroitin Sulphate 200 mg Cap, Leflunamide 20 mg "ab, Etoriocoxib 90 mg "ab, Serratiopeptidase 5 mg "ab, Amoxycillin + Clavulanic acid 625mc Tab, Amoxycillin + Clavulanic acid 10OOmg Tab, Amoxycillin 250mg Cap, Azithromycin 500 Cap/Tab, Furazolidone 100mg Tab, Acyclovir 200mg Tab, Emtricitabine 200 mg + Tenofovir 300mg Tab Lamivudine I50mg+Stavudine 30mg+Nevirapine 200mg tab, Zidovudine 300mg + Lamivudine 150mg Tab, Efavirenz 600mg Tab, Zidovudine 300mg + Lamivudine 150mg + Nevirapine 200mg Tab, Anastrazole 1mg Tab, etc.,
The TANGO study was conducted to assess whether adults living with HIV-1 who had maintained viral suppression for at least six months on a tenofovir alafenamide fumarate, or TAF,-containing regimen of at least three drugs, were able to maintain similar rates of viral suppression after switching to the 2-drug regimen, or 2DR, of dolutegravir plus lamivudine in a fixed dose combination, compared to continuing the TAF-containing regimen.
One generic HIV drug, lamivudine, stood out because of its activity and low side effects.
Lamivudine's efficacy and safety in preventing mother-to-child transmission of hepatitis B: A meta-analysis study
(8-10 ) For lamivudine, the prevalence of resistance rises rapidly, reaching 80% after five years of monotherapy (11) The pattern of rtL180M/M204V is the most common lamivudine-resistant HBV variant, with a prevalence of 60%.
Patients between 18 and 70 years receiving oral antiviral agents (lamivudine, entecavir, or tenofovir disproxil fumarate) for a minimum duration of 3 years due to CHB were included.
In 2010, the World Health Organization (WHO) recommended HBV screening before ART initiation, and the use of ART regimens containing tenofovir plus either lamivudine or emtricitabine for HIV/ HBV coinfection.
Two regimen were there based on Tenofovir:Tenofovir, Lamivudine and Nevirapine Regimen and Tenofovir, Lamivudine and Efavirenz Regimen.
Oral lamivudine (GlaxoSmithKline, Brentford, UK), a US Food and Drug Administration-approved anti-HIV drug, has been suggested as a possible antiviral agent against Ebola virus (EBOV).
Lamivudine (4 mg/kg/day) was given to 29 of the patients who were given treatment, interferon-[alpha] (IFN-[alpha]) (6 MU/[m.sup.2], three days a week) was given to 3 patients at the same dose and both IFN-[alpha] and lamivudine were given to 4 patients.
The lamivudine and telbivudine are prone to develop resistance rapidly.
Group A received a non-nucleoside reverse transcriptase inhibitor (NNRTI), lamivudine, and abacavir.