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Related to lathyrism: grass pea, Vapniarka


A disease of humans and animals caused by eating legumes of the genus Lathyrus and characterized by spastic paralysis, hyperesthesia, and paresthesia.

[From New Latin Lathyrus, genus name, from Greek lathuros, a type of pea, from Akkadian ladiru, type of plant.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Pathology) a neurological disease often resulting in weakness and paralysis of the legs: caused by eating the pealike seeds of the leguminous plant Lathyrus sativus
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈlæθ əˌrɪz əm)

a painful disorder esp. of domestic animals caused by ingestion of a poison found in certain legumes of the genus Lathyrus and marked by spastic paralysis.
[1885–90; < New Latin Lathyr(us) (< Greek láthyros a kind of pea)]
lath`y•rit′ic (-ˈrɪt ɪk) adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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Kohn, "Bone fracture toughness and strength correlate with collagen cross-link maturity in a dose-controlled lathyrism mouse model," Journal of Bone and Mineral Research, vol.
(eds): Lathyrus and Lathyrism. 3rd World Medical Research Foundation, New York, pp 169-171.
BAPN was used to produce local lathyrism in healing of flexor tendon of chicken tendon but treated tissue did not reveal gross changes in physical properties of scar tissue.
It also has a high level of Beta-N-Oxalyl- aminoalanine, a neurotoxic aminoacid in the legume, which is responsible for Lathyrism. Khesari pulse contains 41% carbohy- By Giridhar Jha in Patna CITING hair fall to be the reason behind her extreme step, a 25-year-old woman committed suicide in the Gopalganj district of Bihar.
Its continued consumption in appreciable quantities for a period of 2-3 months causes progressive spastic paralysis of lower limbs, which is commonly referred to as lathyrism. (4)
The pea family, specifically the grass pea (Lathyrus sativus), is also a source of poisonous compounds such as the neurotoxin ODAP, which is responsible for lathyrism, a neurological disease.
BAPN is a compound known to cause lathyrism, a neurological disease by inhibiting lysyl oxidase, the enzyme that initiates cross-linkage formation in elastin and collagen; this action prevents the formation of cross-bonds, strictures, and collagen synthesis [12].
Severe forms of the string halt have been attributed to lathyrism (sweet pea poisoning) in USA and possibly to flat weed (Hypochoeris radicata) intoxication in Australia (Domange et al., 2010; Araujo et al., 2008).
The discovery was serendipitous, an offshoot of research on lathyrism, a progressive paralysis of the legs found in people in China, India, and the Middle East.