lectin


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Related to lectin: lecithin

lec·tin

 (lĕk′tĭn)
n.
Any of various proteins or glycoproteins that bind to the sugar molecules of glycoproteins and glucolipids on the surfaces of cells and are found in most organisms, especially plants. They are used to stimulate lymphocyte proliferation and to agglutinate red blood cells.

[Latin lēctus, past participle of legere, to select; see select + -in.]

lectin

(ˈlɛktɪn)
n
(Biochemistry) a type of protein possessing high affinity for a specific sugar; lectins are often highly toxic
[C20: from Latin lectus, past participle of legere to select + -in]

lec•tin

(ˈlɛk tɪn)

n.
any of a group of proteins that bind to specific carbohydrates and act as an agglutinin.
[1954; < Latin lēct(us), past participle of legere to gather, select, read + -in1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.lectin - any of several plant glycoproteins that act like specific antibodies but are not antibodies in that they are not evoked by an antigenic stimulus
glycoprotein - a conjugated protein having a carbohydrate component
References in periodicals archive ?
OMS721 is Omeros' lead human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2, the effector enzyme of the lectin pathway of the complement system, and is in Phase 3 development for each of IgAN, atypical hemolytic uremic syndrome, and hematopoietic stem cell transplant-associated thrombotic microangiopathy.
Most people have never even heard of them, but I believe lectins are the #1 Biggest Danger in the American Diet," says the website of cardiologist (and "Lectin-Shield" supplement salesman) Steven Gundry, author of The Plant Paradox.
OMS721 is Omeros' lead human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2), the effector enzyme of the lectin pathway of the complement system.
Fermentation and sprouting also decreases lectin content.
There's more than one type of lectin, and different ones can do different things.
3 Broad beans contain lectin, a protein found in many plants, and research has shown that those from broad beans may alter the behaviour of cancer cells in the colon.
An assay using a 3-sulfated core1-specific galectin-4 lectin was recently reported to show superior clinical sensitivity and specificity over a conventional CA15-3 immunoassay for breast cancer (20).
Concanavalin A (Con A) is a glucose-binding legume lectin long-studied and has been used for fractionation and structural analysis of oligosaccharides and glycoproteins (Li, Yu, Xu, & Bao, 2011, Shastri et al.
Additionally, the 601 Patent covers the company's methods of capturing exosomes whereby a patient for exosome capture is identified and an exosome from the patient is bound to a surface that comprises a lectin thereby capturing the exosome.
The 17 chapters explore simple and complex carbohydrates and glycoconjugates; methods of structural analysis of glycosaminoglycans, applications of these methods for identification of lysosomal storage diseases, and participation in the development of Lyme disease; the role of viral envelope protein glycosylation in the pathogenesis of influenza A virus; the application of lectin histochemistry in the diagnosis of lysosomal storage diseases; computational approaches for studying carbohydrate-lectin interactions in infection; the pathogenic effects of altered sialylation of specific glycoconjugates in genetic diseases; sialyltransferase regulation of cancer-associated O-glycans; and the history of pectin study, chemistry, and medicinal uses of pectin.