Gary Woodcock, 30, will be walking 250 miles to raise money for Sarcoma UK after his mother was diagnosed with rare cancer leiomyosarcoma
, which affects soft tissue.
This research had the objective to describe the diagnosis and characteristics of a leiomyosarcoma
in a cockatiel (Nymphicus hollandicus) admitted at the Wildlife Rehabilitation Center (NURFS-CETAS) of the Federal University of Pelotas (UFPel) and necropsied at the Regional Diagnostic Laboratory--Faculty of Veterinary (LRD-UFPel).
Although all of these tumors originate from smooth muscle cells, they consist of different types according to behavior, including benign leiomyoma, malignant leiomyosarcoma
, and intermediate group of tumors called smooth muscle tumors of undetermined malignant potential (STUMP).
Specifically, the study did not meet the primary endpoints of overall survival, or OS, in the full study population or in the leiomyosarcoma
, or LMS sub-population; there was no difference in survival between the study arms for either population.
(LMS) of the thyroid gland is a rare thyroid malignancy, accounting for only 0.014% of primary thyroid tumors.
The plaintiff's decedent, a single woman with no children, experienced a two-year delay in diagnosis of leiomyosarcoma
The common primary cutaneous sarcomas include dermatofibrosarcoma protuberans (DFSP), leiomyosarcoma
, and pleomorphic dermal sarcoma (PDS) (also known as an aggressive variant of atypical fibroxanthoma [AFX]).
 This characteristic immunophenotype has made this tumour a distinct entity, though other non-epithelial tumours of GIT like leiomyoma, leiomyosarcoma
, neuromas, neurofibroma may look similar on H and E stain.
Study 309 is a randomized, open-label, multicenter, active-controlled trial of Halaven in 452 patients with unresectable, locally advanced or metastatic leiomyosarcoma
or liposarcoma (LPS) following treatment with at least two systemic chemotherapies, one of which must have included an anthracycline, and disease progression within six months of the most recent chemotherapy regimen.
The review determined that 1 in 350 women undergoing hysterectomy or myomectomy for fibroids may have an occult uterine sarcoma, and that 1 in about 500 have an unsuspected leiomyosarcoma
. The literature review clearly identified increased risk of uterine cancers and decreased survival when these women are treated with an LPM, as opposed to manual morcellation or en bloc removal.
Based on immunohistochemical and histopathological findings, the case was diagnosed as pleomorphic leiomyosarcoma
. Tumor tissue was not found both in the sample obtained using laser and in the second margin examination.
is a relatively common histologic subtype of soft tissue sarcoma that is usually incurable after development of metastasis .