The human immunodeficiency virus (HIV) is a lentivirus
(a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).
Based on these results, cultured cells transfected with lentivirus
were stimulated with PMA/ionomycin for 24 h in subsequent experiments.
M2 PHARMA-January 11, 2018-F1 Oncology, SSSB Partner to Complete New cGMP Lentivirus
Manufacturing Facility in Shenzhen
Key word: bovine LXR[alpha] gene, lentivirus
, vector construction, gene silencing.
Since more than 80% of XSCID patients do not have a matched sibling donor, the company's researchers have re-engineered a lentivirus
to function as a vector to ferry a normal copy of IL2RG into the patients' hematopoietic stem cells.
To overexpress or knockdown HIF-1[alpha] protein, hemangioma cells were infected with lentivirus
particles overexpressing or with knockdown HIF-1[alpha] plasmids (Hanbio, China) for 48 h according to the manufacturer's instructions.
The study shows that a microRNA-302 mimic, delivered by a specially constructed lentivirus
, was sufficient to enable neural differentiation of mouse embryonic stem cells that lacked Dgcr8, a vital gene for the processing of the more than 2,000 microRNAs in cells.
The genetic modification of the cells involves viral technology, specifically a lentivirus
, which also has regulatory and safety implications.
Equine Infectious Anemia Virus (EIAV) is a simple, macrophage-tropic lentivirus
that infects members of the family Equidae.
They delivered the factors into the cells with a lentivirus
, as used in some forms of gene therapy.
They used a vector called lentivirus
to deliver a new gene to cultured human cells.
The assets acquired by Vigene from Omnia will include a 7,000 square-foot laboratory space, including three cGMP manufacturing suites and one process development laboratory for viral vector production, including AAV, lentivirus