lepromatous leprosy


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Noun1.lepromatous leprosy - a very serious form of leprosy characterized by lesions that spread over much of the body and affecting many systems of the body
Hansen's disease, leprosy - chronic granulomatous communicable disease occurring in tropical and subtropical regions; characterized by inflamed nodules beneath the skin and wasting of body parts; caused by the bacillus Mycobacterium leprae
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* It is an advanced stage of macular type of lepromatous leprosy with easily visible infiltration.
lepromatosis lepromatous leprosy is a travel-related hazard for all US citizens.
Only patients with lepromatous leprosy were included in the study.
Though Tregs in mice express CD25 constitutively, in humans only those with CD25 show suppressive function.10 Leprosy reactions in contrast showed a decrease in Treg cells which paralleled the increase in Th17 population.11 Moreover, there was downregulation of intracellular TGF-[beta].11,12 Most reports showed a reduction in Treg cells in patients with ENL reactions compared with non-reaction lepromatous leprosy counterparts.11,12
He was later confirmed with leprosy on the basis of skin biopsy of these lesions which revealed AFB smear 3+ and was labeled with Lepromatous leprosy and started on clofazamine and rifampicin.
Its clinical spectrum ranges from tuberculoid leprosy through borderline forms to lepromatous leprosy of the Ridley-Jopling classification [4].
Clinical diagnosis of lepromatous leprosy was established on the basis of 2 of 3 criteria set by the World Health Organization (WHO) [1]: hypochromic anesthetic skin lesions and palpable peripheral nerves.
Of these, 13 presented indeterminate leprosy (IL), 15 presented tuberculoid leprosy (TT), and 15 presented lepromatous leprosy (LL).
Antinuclear antibodies are reported in lepromatous leprosy and lepra reactions, varying from 3 to 34% but in low titers (9, 10).
(2004) had similar case numbers with confirmed neuropathic pain, using the same exclusion criteria, clinical presentation (lepromatous leprosy), pain assessment procedures and also the McGill Pain Questionnaire.
On the other hand lepromatous leprosy seen in patients with poor cell mediated immunity tends to cause multiple, asymmetrical skin lesions with irregular margins [3].
Findings are concluded to be consistent with histopathological spectrum of lepromatous leprosy.