Casabiell et al., "Synthesis of leptin
in human placenta," Endocrinology, vol.
The present study aimed to investigate umbilical cord (UC) leptin
receptor (LEPR) levels in PE and to examine the direct effect of leptin
on IL-8 production by human endometrial endothelial cells (HEECs) and human umbilical vein endothelial cells (HUVECs), thus to describe the function of leptin
Researchers know that leptin
, a hormone produced by fat cells, is important in the control of body weight both in humans and mice.
"We didn't know how a high-fat diet or overeating leads to leptin
resistance," Fukuda said.
Blocking the interaction of GIP with the brain restores leptin
's ability to inhibit appetite and results in weight loss in mice.
In reaction to rapid weight loss, the brain seems to go into 'starvation' mode, reducing leptin
levels so your appetite is stimulated, encouraging you to eat more and get fatter.
To the best of my knowledge, this is the first study that fully describes seven polymorphic sites of bubaline leptin
gene in Anatolian water buffaloes.
is a novel and promising molecule in research that may link body weight (BW), body mass index (BMI), and neurodegenerative diseases (5, 6).
In view of intense hyperphagia followed by rapid weight gain, early age of onset, family history of EOO and low level of circulating leptin
, a diagnosis of monogenic obesity due to LEP gene mutation was considered.
The serum concentration of leptin
determines the energy status of the body in adipose tissue.
Kisspeptin and Leptin
levels were measured by enzyme linked immune sorbent assay before down regulation of ovaries and initiation of treatment protocol of ART.Failure of procedure was detected by beta human chorionic gonadotropin 25mIU/ml and cardiac activity on trans-vaginal scan were declared pregnant.
Tomoe Hirota, from Osaka City University in Japan, and colleagues investigated the association between fasting leptin
levels and sleep quality in 182 patients with type 2 diabetes.