lethal allele


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Related to lethal allele: Multiple alleles

lethal allele

n.
An allele whose expression results in the death of the organism, usually during embryogenesis.
References in periodicals archive ?
One of the reasons why it has been difficult to bring microevolutionary experiments into classrooms is the obvious tradeoff between choosing an allele that is strongly selected against, such as a lethal allele, and choosing one that is easy to visualize.
The expected frequency of flightless mutants was estimated according to discrete generation selection against a lethal allele (Crow & Kimura, 1970: eq.
Introduction of a lethal allele into a feral mouse population.
Relative fitness of wild house mice heterozygous for a lethal allele.
Selection against lethal alleles in females heterozygous for incontinentia pigmenti.
Additionally, most t haplotypes carry recessive lethal alleles.
Lethal alleles in Mus musculus: local distribution and evidence for isolation of demes.
3, whereas lethal alleles tend to be recessive (Simmons and Crow 1977; Johnston and Schoen 1995).
Model relating unsound seed and embryonic lethal alleles in self-pollinated pines.
In this paper, we investigate two mechanisms that may help to explain these observations: (1) a high genomic mutation rate to recessive lethal alleles, and (2) selective interference among loci with deleterious recessive mutations under partial selfing.
As noted by Werren and by Donald Waller, even lethal alleles tend to have measurable effects on the fitness of their heterozygous carriers, but several other authors persist in stating that detrimental alleles are recessive.